Anybody know the future of REP 9AC on HBV treatment result recently?

[Skyclimber]

Heard that REP 9AC is a new drug for HBV and it can remove HBsAG at a high ratio. Pls check whether there is new information.

[4est]

http://aasld2012.abstractcentral.com/s1agxt/com.scholarone.s1agxt.s1agxt/S1A.html?&CONFIG_ID=2518&USER_ID=1593989&ROLE_ID=16365&ROLE_TYPE_ID=17&PERSON2ROLE_ID=17804403&WORKFLOW_ID=17&CURRENT_PAGE=BROWSE_THE_PROGRAM&ALLOW_EDIT_INSTRUCTIONS_FL=N&SESSION_ADMIN_PERMISSION_FL=N&REVIEWER_ADMIN_PERMISSION_FL=N&DIRECT_LOGIN_FL=Y&HASH_KEY=yrqbzS8yzVEezNSZD0XqU9xbfCw&STUB_ROLE_ID=0&TIME=1346080075691&SOURCE_URL=http://aasld2012.abstractcentral.com


or go to http://www.aasld.org/lm2012/2012/attendees/Pages/ItineraryPlanner.aspx and click on Itinerary Planner and you ca see the program (maybe not the final one but the latest one)

[StephenCastlecrag]

Is the program for AASLD 2012 out? Can you provide a link?

I am still waiting for the proceedings of ISVLD held two months ago to be published.

[4est]

indirect update:

"  REP 9AC’: A second generation HBsAg release inhibitor with improved tolerability. " - this is the title for a presentation that will came in AASLD in November (no other info available at this moment)

[stef2011]

well if he is a good doctor he must be aware already, it was presented in 2010 conference in berlin and 2011 in san francisco from two different hospitals

here is the thread about it, just look at the hbsag of those who didn t clear yet in 48weeks, it is so low that clearance is certain just  matter of time

http://www.medhelp.org/posts/Hepatitis-B/Add--on-of-peg-interferon-to-a-stable-nucleoside--hbsag-loss-40/show/1616137

[MHMD]

Hi stef,

Thank you for your help, I have one last question

Is the way of treatment you have mention above published or announced? if yes please give me the link for the study or the clinical trail so that I can give it to my doctor in order to convince..

  Thanks again and again..

[stef2011]

yes but it is sequential because you need to rescue some immune response towards the virus, so 1-3 years of tdf mono and then interferon add on

not 48weeks, it is 96weeks and more until hbsag gets und


what do you mean by vit d25oh>60ng/ml?
to have your vitamin d serum checked and it has to be higher than 60ng/ml, dont test in other units than ng/ml because confusing and poor sensibility machines are used.vitamin d test is called vitd25oh