HEP B

[hepbvictim]

I was first diagnosed with HBSAg + in 2003 tested HBV DNA which was undetectable (in 2005). didn't take it too serious for 4 years or lets say didn't know what to do with this??. Now in a routine medical exam, found HBSAg still +, ALT are raised to 120 rest of LFT are normal, HBeAG is negative but then Viral load is 11000 (not sure copies or IU, i know it makes a difference if these are copies or IU). some say should be on treatment other saying not. My doctor want me to undergo a Liver Biosy and I am not ready for this as have no problems or sysmptoms and only came to know about this through routine medical exam. Liver biopsy is scary and side affects and risks, what would you suggest guys??

[stef2011]

you can just monitor if you are not taking any drug, make sure to find a lab that has the new abbott machine for the tests so that you can follow hbsag quantity

the machine is abbott architet for hbsag quantification in iu/ml, the range is 0.05-250iu/ml and for values higer than 250 they must use 1:1000 dilutition.if you see that hbsag slowly decline you can monitor and wait for alinia 6 months results at least but in case hbsag is inncreasing i'd start alinia now

[hepbvictim]

Yes, I will keep watching your Alinia progress. In UK they will never prescribe me so I have to get off label. woudl you suggest start using it now o wait for another blood test in 5 months. just to remind, Viral Load was 168 and HbeAg neg.

[stef2011]

just follow how our alinia is going at 6 months and then 12 months and check that hbvdna and alt stay low
hbe pos or negative alone has no meaning, the hbv state is very complex and needs all tests to understand situation

i only feel safe since they are following me at the research center with all the tests, at the local hospital where i go to take the free drugs don't check anything, just hbvdna every 6 months.
just like the researcher told me: the difference between us and a hospital is the same as mcdonalds and an expert chef that cooks only for you....

[hepbvictim]

Hi Steafno,

Agreed. UK is outdated in research and facilities. Fibroscan is hardly available. They still use old drugs. I would say they are at least 10 years behind you guys.

I am not going to start any treatment but continue with Milk Thistle. drinking coffee aswell.

HBeAG neg with this viral load shoudln't be on treatment anyway.

My Only concern is constantly elevated ALTs.

[stef2011]

sorry maybe i confused with another guy about you being from uk, anyway:
ntz can be found from lupin official distributors, but if you cannot have the blood test it is not possible to start it without having a clue if it is lowering hbsag or not, i'd give it up without that test and just monitor hbvdna and alt/ast

http://www.lupinpharmaceuticals.com/adrsub.htm#product_t
in some countries it is available without prescription, you might ask lupin for it

the group is for assistance and to share results with other members so all community can benefit, we have also contact with some drug makers but they are not helping, to join just PM me

[stef2011]

well be aware that at the moment there is no drug to eradicate the virus and this looks like the only one with high rates but if you start you must be sure about it and have a lab to test hbsag quantity and hbdna pcr otherwise you cannot see improvemnts

the doctor is not needed usually to make blood tests but if in uk you need a doctor for blood tests and they are not willing to prescribe it, i don't see a way out of it

actually i have seen hospitals in the center of london and i think they are very old and outdated in general, even drugs are difficult to find there, so you won't find this test in uk probably, other told me they don't even have fibroscans..