Highly reactive HBsAg

[Mars86]

Dears;

I'm 27 years male , Chronic HBV in immune Tolerant Phase and still Immune Tolerant since I got diagnosed last year in Jan...

I was treated with ETV .5 since exactly 12 month and added TDF in the last three months .. DNA is about 240 iu/ml but HBsAg is highly reactive 130 000 iu/ml ... what is the meaning of this high value ? why it keeps increasing while DNA is going to decrease ?

base line DNA was more than 170 * 10^6 iu/ml ... Normal ALT/AST ..

[stef2011]

very good doctor

[Mars86]

it is positive :)

[Mars86]

Sure stef , I visited my Dr. today , he advised to continue using combo ETV and TDF till next October then will add intf ... he also advised with Echinacea
this supports immune system ...

I'll keep all posted...

[Taj82]

what about your HBeAg?

[stef2011]

too little data on immune tollerant treated patients because you should have not been treated

anyway the good point is clearance of hbv is easier when you will add intf

when I can add it on ? after UND DNA directly ?
follow your new liver specialist which sounds very updated

what is the conclusion of this high value of HBsAg ?
this is good on immune tollerant phase, that means you have no immune response yet and when it will be activated under these drugs hbv will be cleared fast

please update the community about your results it may be easily possible that treating while still immuen tollerant is good to clear hbv, no data about this but my personal view is that it is easier to clear

[Mars86]

actually I left the old doctor who treated me in immune tolerant phase and go to a specialist one who advised with TDF add on ...

I think his next step is addiing intf.

but in your suggession , is it ok useful to add intf. while HBsAg is soo high ?

if yes

when I can add it on ? after UND DNA directly ?

what is the conclusion of this high value of HBsAg ?

Thanks