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1261240 tn?1271520861

hbeg positive

what do you mean if the patient is Hbeg positive  with reactive hepa b please help me
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Avatar universal

hbe positive is a phase of hbv infection with high replication of the virus and can be immune tollerant (no immune response and no liver damage) or immune clearance (immune response but maximum liver damage)

in hbe positive the virus has the maximum tier of all antigens and replication so therapy must be started (only immune tollerant=alt lower than 30men 19women must not be treated)

the only good part of hbe positive is that virus is frre to replicate so it has no mutations and after treatment seroconversion with hbe negative and hbeab ositive can lead to inactive carrier

it is not a good condition to have hbe positive since liver damage is more and less time is needed to reach cirrhosis or liver cancer but time is not the same for anybody, some develop cirrhosis in a couple of years and others decades
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Avatar universal
Anti Hbs -ECLIA Method    10.0    2.0       NON reactive

according to the sensitivity of the test this can be very low antibodies or no antibodies, anyway the protective level is >10mIU/ml so if this gets equal or higher than 9-10 you are seroconverting whatever the test used
Helpful - 0
Avatar universal

HbsAg eclia, this is not a quantity test, make test with abbott hbsag quantitative in iu/ml, for example i made a test with my sister, me 300s/n about 5000iu/ml, my sister 335s/n about 17000iu/ml,these tests have diluitions so s/n or s/co can reflect quantity when very close to cutoff only.if you find hbsag <1000iu/ml and hbvdna<2000iu/ml you are inactive carrier for the moment
Anti Hbc IgM -ECLIA Method   cutoff 1.0  (the cutoff for active disease is 0.2s/co)         0.050 so you should be inactive

the antibodies hbcab Igg and hbeab are too low to clear the infection at the moment, you should be cronic but you have to know if your hbsag is positive for more than 6 months

you need to check hbvdna pcr and alt/ast

so check hbsag quantity, hbvdna pcr, alt/ast and if hbsag is positive for more han 6 months.best therapy if you are confirmed inactive is nitazoxanide

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Avatar universal
GOOD DAY!!! sa inyong lahat,,,,
paki explain nmn poh sken kung ano ung lagay ng sakit ko kung malala na poh ba ang hepa b ko?

ito poh ung result ng profile ko..
                                      CUT-OFF VALUES    PATIENT VALUES
HbsAg w/titer -ECLIA Method       1.O                       3,229              REAC .
Anti Hbs -ECLIA Method              10.0                      2.0                  NON
HbeAg -ECLIA Method                      1.0                     0.125            NON
Anti Hbe (reverse)   ECLIA Method    1.0                     0.004            REAC
Anti Hbc IgM -ECLIA Method             1.0                       0.050          NON
Anti Hbc IgG (reverse)                       0.739                   0.411          REAC

whats my result? acute or chronic? answer me pls... many thanks,,,

reply poh kayo,,, maraming salamat poh  god  bless sa ating lahat sana gumaling na tayo sa sakit na ito..
Helpful - 0
Avatar universal
nitazoxanide (alinia, nizonide), alinia more than 2000usd per months according to the pills you take per day, nizonide less than 200usd per month at max dose
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1261240 tn?1271520861
what ntz ?and how it cost?
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Avatar universal
check the community and you  ll find the answers, more tests are needed, but if infection is active (very probable in hbe pos) best strategy is:
ntz 4 weeks after ntz+interferon (better seroconversion rates) or instead interfeon/after inteferon therapy is finished ntz+tenofovir
Helpful - 0
1261240 tn?1271520861
there is a chance that he will be cured? how the therapy done? what is the medicine ?

thanks a lot .....
Helpful - 0
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