Amazing news for null responders

[evangelin]

This was already posted by SusieS2010 on another thread but this seems so good it needs it's own headline.  I will just post the first part but there is a bunch more  you can google for.
Ev

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Reported by Jules Levin
EASL 2011 April 2 Berlin Germany

Presented by Anna Lok

from Jules: this is the biggest story & news to come out of this meeting, needless to say, and the biggest advancement in medicine in 50 years. In this study 4/11 null-responders receiving BMS-790052 (NS5A inhibitor) + BMS-650032 (protease inhibitor) alone for 24 weeks achieved SVR12 & SVR24. The presentation says "HCV infection can be cured without interferon & ribavirin". BMS-790052 & BMS-650032 with peg/RBV for 24 weeks: 10/10 patients achieved SVR12 & 9/10 achieved SVR24: "QUAD therapy can result in a high rate of cure in this difficult to treat population" (1 patient < LLOQ at week 24 post treatment undetectable on retesting 35 days later). This is the proof of concept we have been waiting for that at least some patients can be cured without peg/rbv, now these are the hardest to treat patients null-responders.

[eureka254]

Thanks to both you and SusieS2010 for highlighting that very encouraging information... it's been an especially long wait for null-responders, and hopefully the upcoming data will give re-affirm this particular trial's response rate.  Wouldn't 100% be wonderful! ~eureka

[Trish77]

It's okay, Ev....I think we get the idea. :)

[evangelin]

I  am sorry, I need to rephrase that.  This is amazing news for everyone with hepatitis c.  I was thinking a little narrowly  when I posted that.  
Ev

[Trish77]

That is BIG news.  I have someone I will love to share this with.  Will look up that presentation.  Thanks for the repost, Ev!!!

Trish