Aa
Dangers of Alpha Lipoic Acid IV Therapy !
Here is just one of the many dangers of ALA IV therapy:
This is from Pubmed which is considered to be very trustworthy by the medical community.
http://www.ncbi.nlm.nih.gov/pubmed/19616616
"We conclude that large doses of lipoic acid displace sulfhydryls from binding sites, resulting in depletion of serum cysteine, but also pose a methylation burden with severe depletion of liver S-adenosylmethionine and massive release of S-adenosylhomocysteine. These changes may have previously unrecognized deleterious (harmful) effects that should be investigated in both human disease and experimental models"
This is from Pubmed which is considered to be very trustworthy by the medical community.
http://www.ncbi.nlm.nih.gov/pubmed/19616616
"We conclude that large doses of lipoic acid displace sulfhydryls from binding sites, resulting in depletion of serum cysteine, but also pose a methylation burden with severe depletion of liver S-adenosylmethionine and massive release of S-adenosylhomocysteine. These changes may have previously unrecognized deleterious (harmful) effects that should be investigated in both human disease and experimental models"
Your platelets are the same shortly after tx as they were before tx.
INF messes with your bone marrow where platelets are produced
which is why they often drop during tx.
I would expect your platelet count to improve now that the virus is
gone and your liver can heal.It takes time.
b
INF messes with your bone marrow where platelets are produced
which is why they often drop during tx.
I would expect your platelet count to improve now that the virus is
gone and your liver can heal.It takes time.
b
How long ago did you stop drinking ?
Both GGT and AST are sensitive to alcohol. Yours are within normal range
however according to my experience your GGT could be lower and your
so does your AST.
If you are going to see Dr. Berkson with normal labs like that you are
going to be one of the healthiest patients there......lol.
Regarding your cholesterol ....what does your diet look like ?
Again , when you drink alcohol that is the first thing your liver will
turn into energy . Everything else you eat while ingesting alcohol will
be turned into fat and stored and over time cause fatty liver
Here is what I would do with that lipid profile:
NO ALCOHOL , no grains (pasta , breads, flour) , no sugar , no omega 6
fats (vegetable oils)
Instead try to get your carbohydrates mostly form vegetables , your
fats from butter,olive oil, coconut oil (saturated fats are ok even healthy in moderation) , protein from poulty , fish , meat. Nothing processed and
take about 1-3 gs/day of high quality Omega3s (fish oil)
Add to that an exercise routine and your lipid profile will turn around.
If you do cardio exercise it should also better circulation and maybe
help with your palms.
How high are your triglycerides ?
Personally so far I don`t see any reason why you need to spend $$$ in ALA Iv`s.
b
Both GGT and AST are sensitive to alcohol. Yours are within normal range
however according to my experience your GGT could be lower and your
so does your AST.
If you are going to see Dr. Berkson with normal labs like that you are
going to be one of the healthiest patients there......lol.
Regarding your cholesterol ....what does your diet look like ?
Again , when you drink alcohol that is the first thing your liver will
turn into energy . Everything else you eat while ingesting alcohol will
be turned into fat and stored and over time cause fatty liver
Here is what I would do with that lipid profile:
NO ALCOHOL , no grains (pasta , breads, flour) , no sugar , no omega 6
fats (vegetable oils)
Instead try to get your carbohydrates mostly form vegetables , your
fats from butter,olive oil, coconut oil (saturated fats are ok even healthy in moderation) , protein from poulty , fish , meat. Nothing processed and
take about 1-3 gs/day of high quality Omega3s (fish oil)
Add to that an exercise routine and your lipid profile will turn around.
If you do cardio exercise it should also better circulation and maybe
help with your palms.
How high are your triglycerides ?
Personally so far I don`t see any reason why you need to spend $$$ in ALA Iv`s.
b
Not so sure about the difference between the ASH FibroSure and the Nash FibroSure, but my experience was this: I had a Fibrosure test done last year, and it had me at .77, and I was told (to my shock) that I had cirrhosis.
My platelets were at 122, my Alt was 478 (AST 299), and the Alpha-Macroglobulin was high, at 4.3, and the Haptoglobin was low, at 26.
I then had my first biopsy done, and was told I had grade 3 inflammation, and stage 2, fibrosis.
I went into Tx, (genotype 1) and within 4 wks, my virus was Und, and Ast/Alt normal again. My platelets dropped hung at 90 during mid Tx, but dropped to 66 at EOT.
At 3 months post tx, my platelets had then risen back to 122.
My guess is I actually had Stage 3, and the Tx was psushing me towards cirrhosis. I am hoping to have normal platelets at my 24 wk post test (I was Und at 12 wks post luckily).
But still, I wonder...are the low platelets an indication that I am cirrhotic now, or a sign that I have another (more terrifying) problem?
My platelets were at 122, my Alt was 478 (AST 299), and the Alpha-Macroglobulin was high, at 4.3, and the Haptoglobin was low, at 26.
I then had my first biopsy done, and was told I had grade 3 inflammation, and stage 2, fibrosis.
I went into Tx, (genotype 1) and within 4 wks, my virus was Und, and Ast/Alt normal again. My platelets dropped hung at 90 during mid Tx, but dropped to 66 at EOT.
At 3 months post tx, my platelets had then risen back to 122.
My guess is I actually had Stage 3, and the Tx was psushing me towards cirrhosis. I am hoping to have normal platelets at my 24 wk post test (I was Und at 12 wks post luckily).
But still, I wonder...are the low platelets an indication that I am cirrhotic now, or a sign that I have another (more terrifying) problem?
B-
continuing from the post:
Last Ash Fibrosure:
Haptoglobin was in normal range at 67.
A2M was 318 (normal is 110-276)
APO-A1 was 109 (normal is 110-180, so no biggie there).
All other Ash Fibrosure markers were within normal ranges.
I do have AST/ALT inversion: AST of 29 and ALT of 25. According to my doctor when AST is the higher number it's indicative of some degree of liver damage - even when both values are within normal limits.
My lipid profile is a bit abnormal:
LDL-P is high at 1400
LDL-C is high at 131
HDL-P is low at 28
HDL-C is low at 38
BUN is 14
Creatine is low-normal at 0.80
If there's any other score that's relevant just let me know - thanks,
P-
continuing from the post:
Last Ash Fibrosure:
Haptoglobin was in normal range at 67.
A2M was 318 (normal is 110-276)
APO-A1 was 109 (normal is 110-180, so no biggie there).
All other Ash Fibrosure markers were within normal ranges.
I do have AST/ALT inversion: AST of 29 and ALT of 25. According to my doctor when AST is the higher number it's indicative of some degree of liver damage - even when both values are within normal limits.
My lipid profile is a bit abnormal:
LDL-P is high at 1400
LDL-C is high at 131
HDL-P is low at 28
HDL-C is low at 38
BUN is 14
Creatine is low-normal at 0.80
If there's any other score that's relevant just let me know - thanks,
P-
B - i'd sent sent you a separate private msg that included my AST, ALT, etc.
Did you ever have red palms??
Did you ever have cold extremeties (esp. hands)??
Did you ever have red palms??
Did you ever have cold extremeties (esp. hands)??
my labs are very similar to yours only that my GGT is lower 16.
It was in the 30s while infected and abstinent from alcohol and
60 while socially drinking while unkowningly infected.
Anyway on the FibroSure my A2Ms were high and haptoglobin low.
Everything else normal . My hepa Dr. Doulas Dietrich (he used to post
on MH years ago and also had HCV at some point and did tx )
told me to go see a hemotologist if I was worried about it but that
my liver was totally just fine. Something is stressing my reds and strenuous exercise which I enjoy can do that.
What is your AST ?
Don`t get me wrong but based on my personal experience if the Fibrosure is the only thing that says cirrhosis I would not trust it.
BTW , not everyone gets cirrhosis from drinking alcohol but daily consumption is no good.
It is what we do every day that eventually ends up killing us not so much what we do
once in while.
If I were you believing I was boderline chirrhotic and drink alcohol on a daily basis
than I would be more scared about HCC risk than fibrosis.
b
It was in the 30s while infected and abstinent from alcohol and
60 while socially drinking while unkowningly infected.
Anyway on the FibroSure my A2Ms were high and haptoglobin low.
Everything else normal . My hepa Dr. Doulas Dietrich (he used to post
on MH years ago and also had HCV at some point and did tx )
told me to go see a hemotologist if I was worried about it but that
my liver was totally just fine. Something is stressing my reds and strenuous exercise which I enjoy can do that.
What is your AST ?
Don`t get me wrong but based on my personal experience if the Fibrosure is the only thing that says cirrhosis I would not trust it.
BTW , not everyone gets cirrhosis from drinking alcohol but daily consumption is no good.
It is what we do every day that eventually ends up killing us not so much what we do
once in while.
If I were you believing I was boderline chirrhotic and drink alcohol on a daily basis
than I would be more scared about HCC risk than fibrosis.
b
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