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Geno 1B. On Olysio & Sovaldi. Started 1/24
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Geno 1B. On Olysio & Sovaldi. Started 1/24

So far so good except really exhausted...
Anyone else just starting?
Tags: exhausted
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I will continue to pray for your healing.  My husband will be taking the Sovaldi and Ribivarin, he also 1b with stage 4 cirrhosis.  My concerns are that his platelets are in the 70's.  and i work full time should i take some time off from work to be by his side?  also is this the same treatment you are taking?  I know that there is another drug called Olysio.  
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Hi There,
I started the same 2 pill treatment on 1/10/14.  I am 61 years old - 1b with stage 4 cirrhosis.  And this is my 3rd attempt to kill Hep C.  Last treatment was with Incivik, Pegusus and Ribavarin and it almost killed me with the nasty side effects.  Spent most of 6 months in bed wondering if I would ever get out of it again.  1 year after that treatment I was ready to try these new drugs.... so glad I did!  I got my 2 week labs back today and everything is normal range with no indicator of heading towards anemia.  (last treatment had a few transfusions).
Side effects ???  MINIMAL!  I have had a few chemical induced headaches that hit hard - but all I have to do is take 1 extra strength Tylenol and it is gone within 20 minutes completely!  1 morning I had a little nausea for about 10 minutes- fleeting with no vomiting.  Energy is better if I stay active.

You might try to really push your activity and see if it helps.
We are so fortunate to have these drugs and I believe we will see the results we pray for.
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! I just wanted to say, I am so happy for both of you!
This is so great that doctors are able to do this to help those who just can not try anything else.

My best to both of you!
Dee
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Avatar_f_tn
I will continue to pray for your healing.  My husband will be taking the Sovaldi and Ribivarin, he also 1b with stage 4 cirrhosis.  My concerns are that his platelets are in the 70's.  and i work full time should i take some time off from work to be by his side?  also is this the same treatment you are taking?  I know that there is another drug called Olysio.  
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I do not take Ribavarin - just Sovaldi and Olysio because my last attempt at treatment caused severe anemia...... no more Ribavarin or Interferon for me.  To give you my opinion on you taking time off..... if your hubby starts feeling week and weird and dizzy he will probably know anemia is headed his way.  If you work close to where you live and can get home fast should he need you then that is your best approach going into this.  Has he talked with his doctor about doing just Sovaldi and Olysio?  Maybe this should be discussed first.  The studies and results are quite amazing... especially for us with 1b and stage 4 cirrhosis that are prone to low blood count issues.
Keep us posted and do not be afraid to be your own best doctor with research and knowledge on your side!
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Good luck! Keeping fingers crossed for you!.  I too just started those two drugs a couple of weeks ago - but I'm also taking ribavirin. Not much fatigue to mention (fortunately).  You should try to keep very well hydrated on these drugs!

(I was going to report not many side effects, but I have developed jaundice because of elevated bilirubin from the the Olysio.)

Mark
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Ready to start my 3rd attempt to treat Hep c. did the riboviran and interferon twice and it almost killed me . Jut got approved for riboviran and sovaldi for 12 weeks. I also have type 1b with stage 4 cirrhosis. good luck to all I start this Thursday.
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Hi and praying it works for you too! I am also 61 and got pericarditis from the Interferon/Ribavirin treatment. I am so grateful and feeling rally positive about these 2 new oral drugs!
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My treatment is brand new. Good luck to your husband! He may feel okay during the treatment...
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Thank you Dee!
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Best of luck to you Mark!
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Good luck to you too!!
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Good luck with your tx. I am 1b also.
Is this your first treatment?
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I tried Interferon and Ribavirin and I was also in a trial that did not work. You?
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No I am tx Naive but interferon intolerant due to other health issues. Hoping to get on a similar combination to what you are on.
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How are you feeling? I hope you are doing well.
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Hope you are feeling good.  My husband started his treatment and he's feeling fatigue and his MELD score went from 11 to 14.  He's on Sofosbuvir 400mg and ribarvirin 600.  not sure if its the same treatment you are taking.  Dr. said his viral load went down to 271 to 150.  but his billrubin increased to 3.8.  so confused, not sure if its good news.  I hope that you are doing good, don't give up and keep the faith.
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I started last Friday, I feel exhausted but can't sleep!
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I am moving right along and no side effects really.  No viral load at the 4 week mark and now have just 5 more weeks to go.  Hope everyones treatment can be as easy as mine has been and that we all succeed this time!
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So happy for you!!!
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Hi I am Brenda. I will be 60 yrs old next month and have never treated. What are you treating with? Is there any treatment for 1A or is the non inteferon for other types? I go to a hep c doc this Thurs. I have not been to see one in a couple of years but my viral load is extremely high I found out but no other problems so far. I am hoping to treat soon.
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There are many new treatment programs right now and hopefully you will have a doctor that matches you with the right one.  I think it is important that you get this virus gone before it turns your liver cirrhotic and it will lead to lots more issues at that point.  This is a great time to kill that dragon if you can!
Best of luck and stay on this forum..... you will make friends and learn a ton of stuff!
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Yes I used to come here alot, but quit for a few years trying to ignore my Hep C. I have alot of probs with fibromyalgia and arthritis. I just hope being genotype 1A will not it harder to find a good treatment without the interferon. I should find out something thurs at my appt.
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Started 1/2/14

Good luck to us all..
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Just noticed....I'm on Sofos & Riba...

I must pay attention
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Good luck tomorrow!
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thank you Dee!
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Good luck to you!
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Been on treatment Solv/Ribv and starting my 7th week of 12.     Geno 2, cirrhosis, never treated.     Cleared the virus at 2 weeks.    Watching hmg as started 14 and blood work at week 6 was 11.   Told after week 4 it usually levels out.      Was 11.2 at week 4.    This med has been so easy with few side effects.     1st couple of weeks was semi emotional, week 4 was a little nausea, and now can't really tell I'm on a drug.     Like taking a vitamin.    Have continued to be virus free.   Insomnia can be an issue but if you take the med right before bed not a problem.   Can't say enough about how doable this drug is and how grateful to be on it.    Hope soon everyone will be able to have access to these drugs since they are very life changing.    For anyone starting treatment with this regimen or similar want you to know that side effects are so minimal and the outcome makes it incredibly worth it.   Hope in the near future hep c will become a distant memory for all.     Kim
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That is really great to hear Kim!!!
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Thats great, my husband is on his entering his 12 weeks, the virus was undetected after the 2nd week.  He still has the issue of Cirrhosis of the liver.  I'm just wondering what happens next.  Has anyone been at that stage, how long it will help before a transplant?  Praying for healing for all.  
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Happy to hear your husband is undetected as of week 2. That's a wonderful result.  Does your husband have compensated or decompensated cirrhosis?

This link posted by another member  (thanks, Jimmy!)
will provide you with good information about the difference between the two and other important information about how advanced his liver disease may be.

http://hepatitisc.uw.edu/pdf/evaluation-staging-monitoring/evaluation-prognosis-cirrhosis/core-concept/all

Anyone who has (ESLD) end stage liver disease with decompensated cirrhosis should be evaluated for transplant by a hepatologist at a transplant center. HCV treatment should also be carefully monitored.

Nan

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Avatar_m_tn
I looked at your prior posts here
Jan 28, 2014 My husband will be taking the Sovaldi and Ribavirin, he also 1b with stage 4 cirrhosis.  
Feb 23, 2014 My concerns are MELD score went from 11 to 14.  He's on Sofosbuvir and ribavirin 600 mg.  Dr. said his viral load went down to 271 to 150.  but his bilirubin increased to 3.8.

How are those numbers doing now?  "the virus was undetected after the 2nd week" so it went up after that? Usually it's less than 25 but could be different depending on the test used.  My GT2 12wk same meds are considered undetected under 25 during tx.

What is his latest MELD score and is he on a transplant list?
Has your husband been diagnosed with cirrhosis compensated or decompensated?  Is he being treated at a liver transplant center?  Other serious problems like HCC or other?  How long is treatment projected to last if no counter indications to stop?

My knowledge is very limited and non professional about this type of situation but with more info members may better be able to help. HectorSF is one of the best and with personal experience.

Just a suggestion it might be better to start a new question and list some your husbands specific conditions and ask the question.  Since this thread is over 2 months old and about Olysio & Sovaldi.

Use what every you think is best for a title. I made this rough example up in a minute.
What's next, Husband wk 12 of x, Sovaldi Ribavirin, transplant? GT1b  

I really hope and pray that your husband gets the best treatment, care and lives for many years.
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Sending prayers to you and I wish you and your husband well!
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I just finished 12 week treatment and not only is my Hep C undetectable, my Rheumatoid factor went from high to normal after 30 years! Also I don't feel fibromyalgia pain anymore. Amazing treatment! I am so grateful. Good luck to you all! Amye
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Happy for you!

Nan
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Wow congratulations to you Amye !

I am 10 weeks Sovaldi olysio, also undetected, I am curious to see about the RA I also have it goes, that would be a great accede benignity!
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Total misspelling spell check
I said I have RA too
And hopefully it will go away for me too!!!
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OMG.    That's great news.    I also feel as tho I may have RA, but never been tested.   Thought it was in my head that the RA felt better.    Had no idea that treatment could affect that.     Ayme many congrats with finishing treatment.     It's been 2 weeks med free and feel better everyday.     Amazing.....My hmg is slowly returning to normal.     Keep us posted on your follow up care.     I get blood draw May 5th,  4 weeks post treatment.    Will let  you know the outcome.     Again, so very happy for you.          Kim
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Good luck to you! Please let me know!!
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Thank you Kim! So happy for you as well. I would love to know if your rheumatoid factor is now normal. Thank you. I hope it is normal for you!
I was told after I forget, 3 or 4 months after treatment ends and your virus is still undetected, you are cured!! I am having my 12 week bloods on May 1st. Amye
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Hi Amye I will let you know bout the RA
Quick question
Are you still fatigues, and how long are you off treatment?
Cause I have 11 days left, and I am so so so tired in bed, hoping it goes away right after treatment over, but who knows, how about you?
Thanks :-))
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Thank you!
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I ended on Friday, so it is 4 days and I am feeling less tired. Maybe you need to have your blood cell count taken. Are you sure you are not anemic?
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Bloods are good, no Riba, just Sovaldi and olysio

But I have autoimmune disease, primary Bilary cirrhosis and hypothyroid , so I think it maybe  that making it more pronounced, just saw at the top of the thread you first wrote you were tired as a side effect in the beginning so I wondered if that went away after you stopped treatment, I am hoping I will :-)
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omg! i have such pain and fatigue..every muscle just hurts , every joint and fiber of my being.. glad you feel better yippeee!

i feel confident that if i get the dragon gone i will feel better! i read other posts that people had more energy and less pain after these new interferon treatments

hope to start sov/oly next week…

treatment naive
1a
TT
f 2 - 3
vl about 900,000 - 1,200,000
ast alt in the 40's

i am ok but have just diagnosed with ckd 3  ugh..waiting for biopsy report they say it may be the hcv causing the kidney problem,… ugh..glad that my new doctor  found it…i want to know what happened to stage 1 and 2…the old docs dropped the ball on that and i am very mad.

onward to curing this and hope stopping any more kidney damage..

and i thought that i only had to worry about my liver..what the heck?
are the previous doc's quacks? like they never read any of my labs from 2008 till now.?  



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I wish I could say that I felt as good today as the first week of treatment - I am on the 7th week of Sovaldi/Olysio regimen.

But I actually have felt pretty bad the last 2 weeks. Super fatigued, head aches, achy joints and muscles. It's like the flu without the fever and runny nose and coughing

Still, I'm more than 1/2 way through my treatment and I have heard some say that it gets better after the 7th week?


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Hi hep c and me
I know what mean, everyone says they feel so good, well I don't, but I don't want to discourage any one from treatment
But I do feel sick, and very tired

I am 11 days away from finishing olysio and Sovaldi though and feel blessed to have taken it and am undetected

But you are not alone I feel same as you
Xo
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Hi,
It subsided slightly. I feel better every day. Also just the two pills
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Great I am glad you are feeling stronger everyday

I am right behind you, 10 days to go :-))
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I hope it gets better for you. Just keep in close touch with your doctor...
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I am so sorry. I hope you are now getting the care you need!
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