Stopping at week 36

[Tekelcat]

Hi, I can't do it any more. 24 weeks of Pegasys and Ribavirin and Gilead GS5885 and Gilead 9451. Didn't UND until week 6 which according to the trial protocols means I must continue Pegasys and Ribavirin for another 24 weeks. Now at Week 36. Still UND, but have spent the last two weeks vomiting and nauseous all the time. I can't go to work, can't do my research and write my book and the sx have been getting worse. Tried Maxolon and Zofran. No effect and just made me really sleepy or gave me blinding headaches. last night at 2 am I retching blood into the toilet and at that point I decided, enough. No more. I'm out. maybe with UND since W6, the TT allele, and the Gilead drugs, I'll stay UND, but if not, that's. Just the way life goes. I don't have serious fibrosis and I need now to get healthy again, get back to my career. thoughts?

[Idyllic]

I am so glad you are trouble shooting what it could be about your existing routine that might be contributing to how awful you feel. I hope so some changes and the temporary dose adjustment gets rid of your nausea.

I know we are supposed to take the Riba with a small amount of fat but somewhere along the way I guess I got out of the habit of doing that. So here I am taking all these different antihistamines and antiemetics to treat the sides and it could be because I am not eating. I think your doctor's theory about a "loop" makes sense. And maybe what you are doing could be considered breaking the cycle.

I hope you post again to let us know if this worked and how you are feeling. I know it must have been overwhelming feeling sick and not being able to focus and I am glad you feel more optimistic. ♫

[BoceprevirGal]

  Yes, I totally agree with your Hepa Doc, about the not eating food with Riba cycle, and nausea. I noticed this, very early on, in Tx. It is VERY important to take the Riba with food, the more nutritious, the better!
   It was good detective work, on both you and your Docs' part, to figure out that yr week-end of traveling started the nausea cycle~
  I'm glad that a solution has been found, good luck~

[willbb]

FYI: Hepa seems to think that we can get caught in a loop with the Riba and nausea. He tells me that if we forget to take it with food more than a couple of times in a row, the nausea and vomiting can start and this begins a loop: nausea and vomiting stop
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No -one here is walking in  the OP.s shoes ,however it seems  many here have given excellent advice as usuall that also seemingly  correlates with what his doctor has advised.

Hope you are well..
Will

[pcds]

No one on this site is walking in your shoes.  36 weeks is a longtime.  Do what you feel you must.  

[flcyclist]

Wow.  Scary indeed.  Great to hear the nausea and vomitting has subsided for now.  Hope you'll be able to complete tx to give you the best chance for SVR.  You'll soon be into the single digits and the weeks will click away.  You're not too far from eot.   You certainly wouldn't be the first who's had to stop early due to major complications if that has to happen.  Wish you the very best carring forward.  

[bamabred]

Hi i went thru 2 treatments so i know how you feel,anyway this is not about me but you,you will be in my prays.It seems like your riding the fence hu?You know your own body better then any dr.,i wish you the best of luck and anything else that will help you!  :)