Telaprevir Launch Could Be Delayed to 2012

[Bill1028]

This sucks!

http://money.cnn.com/news/newsfeeds/articles/apwire/da3e9a9e4c40232cc4c40734b0762a6c.htm

[merryBe]

I just hope all those "naked shorters" realize one day they'll stand naked before..... Him....with no shorts, or jockeys either, to protect them....  : ))))))))))))))))))))))))))))))))))))))

[Willy50]

Ooops,  you said it clearly but I missed it.

[Andiamo1]

The stats I was referring to were for my SOC treatment prior to the Prove 3 trial.  On SOC, I continued undetectable until EOT and then relapsed after one week off treatment.

On prove 3 my viral load dropped from 8.2 million to <30 in one week and undetectable in two weeks.

Eric

[Willy50]

http://biz.yahoo.com/bw/080107/20080107005882.html?.v=1

Vertex Pharmaceuticals Reports Progress in Development of Investigational HCV Drug Telaprevir and Provides Business Update
Monday January 7, 8:01 am ET  
- Formal European scientific advice obtained for telaprevir development program -  
- Meeting scheduled with FDA for January 2008 on Phase 3 trial design and recent data -  
- Next-generation HCV protease inhibitor and two investigational compounds for cystic fibrosis in clinical development -


CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX - News) today announced its key business objectives for 2008 and provided an overview of recent developments, including highlights from research and development programs, in conjunction with the 26th Annual JPMorgan Healthcare Conference in San Francisco. At the conference, Joshua Boger, Ph.D., President and Chief Executive Officer, and Kurt Graves, Executive Vice President, Chief Commercial Officer and Head, Strategic Development, will today review Vertex’s HCV product development and commercialization strategy. A live webcast of this presentation will be available on Vertex’s website, www.vrtx.com, today at 2:00 p.m. PST (5:00 p.m. EST).
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The article is too long to post but it is juicy and worth a look,  Boger does the presentation today and they also mention that they started dosing with VX-500.  Looks like it will be a good presentation.

Willy

[Willy50]

Agreed with Mike.  You qualify for an EVR by either account.  Frankly, wouldn't you be an RVR as opposed to an EVR?  After all, you cleared and stayed clear by week 2. (the qualifier for RVR is @ 4 weeks)

By the way....there is a Vertex teleconference today at 4 pacific time.  I hope they give us a little insight into what's going on.

Best,
willy

[mikesimon]

A 2 log drop or undetectable by week 12 is classified as EVR. The newer thinking based on studies is that complete EVR (undetectable by week 12) or cEVR is more predictive of achieving SVR than EVR so, perhaps we should alter our thinking and our decision making with that distinction in mind. Good luck to you, Mike