Cindy, don't be sorry about that!! That's what this forum is for - we ALL had alot of questions and we ALL came here for information and learned from each other doing EXACTLY what you are doing. This is a place for people to come to get information and support on dealing with all the various aspects of dealing with their Hep C.
Treatment is not something anybody should take lightly - serious drugs, serious undertaking. We were all in your shoes at one point and now some of us are SVR. Thankfully we had this place to post our questions and concerns and get support. Post your questions and people will help where they can. NO worries AT ALL.
Trish
I am sorry that i ask so many questions.And I surely dont want to become a nuisance.I just have become so educated by you all that I find myself overwhelmed with the what -ifs and all the tx scenarios.Im sure it took you all time to get to know the things you all do.and I admire you all for that.Thanks for teaching me.You are ALL awsome !! cindy
Cindy, if you have any questions remaining on this that you need answered so that you can make a good decision, feel comfortable with the direction you're taking or allow you to advocate for yourself better with your treatment team and doctor, by all means - ASK. If anyone else reading this has questions for themselves as a result, by all means - ASK. We are not doctors (well..with one exception now) but we share experiences and sometimes it helps a great deal to bounce things around and with other people and we do it here all the time. If you find it beneficial to help give you greater clarity - that's what this forum is great for.
Good luck with sorting these things out for yourself as you go along.
Trish
I'm just not sure how much more we can debate this issue than we already have.
At this point, I imagine the best thing to do is consult your doctor - get a second opinion from one of the top doctors in hepatitis and then do what they say.
There are no crystal balls here so you just have to go for it and then see what happens. Debating it over and over doesn't help the outcome at all.
All in all, with a 4 week RVR, SOC and a high VL, I'd resign myself to the fact that 48 weeks IS the best treatment for the shortest duration. The exception would be if you had an RVR and your side effects were debilitating enough to cause you to consider ending treatment sooner.
The other predictor of success is how soon you go UND when on treatment. *IF* it were available to me and if I were thinking of shortening duration at all or simply so that I would have as much information about my status as possible to make decisions throughout, I would get a PCR weekly for the first 4 weeks. That might seem extreme to some, but knowing WHEN you went UND in the first 4 weeks is good information.
Now, the logistics of actually GETTING weekly PCR's might not be realistic or possible for a number of people....just saying, if I could go at this the way I'd want to, that's what I'd do the first four weeks.
Trish
Not so much that the "American and European populations" are so different as that the euro-geno1 is slightly easier to cure than American geno1 - slightly different sub'sub'genotype. Drove docs crazy for years trying to figure out why European studies always came out slightly better than American ones.