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1253246 tn?1332073310

Undecided about options

Trying to question the scenarios available to me since I have the CC allele

1-If I do the standard soc and rvr at 4 weeks would I only have to do 24 weeks?Or  will I be doing 48 regardless?
I have a high VL so this would be a chance Id be taking,but I have read that high VL's were also associated with the CC gene.Maybe this is why my dr said he knew I was a CC? It was an educated guess but he was right.
I would like the best possible tx with shortest time.

I know Ive already talked about this but im just going crazy thinking bout all this  cindy
Thinking OUT OF THE BOX  as I always do !!!!
28 Responses
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979080 tn?1323433639
IR starts before diabetes as far as I know . You can have perfectly fine blood sugar levels and still be IR.An easy way to check it is on your next blood test include a fasting glucose and fasting insulin test from the same blood draw. You can calculate your Homa (IR) score from those 2 numbers
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1253246 tn?1332073310
You mean diabetes?I can have that checked out.High viral load is also associated with the CC allele from what I read. Thanks for the info cindy
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979080 tn?1323433639
Something I wanted to mention the other day but forgot high viral load sometimes is associated with insulin resistance.
IR is a negative for INF tx.
This is something that you can find out relatively easily and  possibly take care of before
starting tx.
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Avatar universal
I mentioned to you what was said to me: paraphrasing; - Do you know how lucky you are to be a CC?  Okay, then why are you doing a study when 24 wks is about to become the SOC for CC's?-  

This was said to me by a PA at a well experienced research university but it was said without any substantive facts being given to me.  That doesn't mean that there are no facts and if I were you, I'd follow the good advice you've received - do more research, question your doc, and carefully weigh your liver situation and how quickly you need/want to move forward.

Good luck on a difficult decision,
Susan
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Avatar universal
"I would like the best possible tx with shortest time. "  
--------------------------------------------------------------------------------

Cindy...I think we can all relate to that. Unfortunately at this time there just is no 100%  guaranteed answer for what is best for each person  The questions for those of us treating currently and thinking of treating in the near future are certainly getting more diverse. I would imagine down the road it will be much clearer when all the data from current trials,data from the affect of having the different alleles.and most importantly  what the data will show from the people that will be treating in the future on the new meds(in regards to efficacy,side effects and time frames for tx.etc.) all shows.

I guess this is sort of a long winded way of saying that ,right now there is no definitive right or wrong answer to the best course of action seeing as we are  currently at the cutting edge of all that data

The fact remains ..you have very good predictors for success  and you mentioned in your previous post that you are conferring with a knowlegable Hepa that has lots of experience with tx. as well as knowledge of results from trials.

You have received some great opinions from folks here ..combine that with the experts advice...make a decision and don"t look back.

Hope that helps some ..and doesn"t confuse further.

WILL



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Avatar universal
Sounds like you have some good imput on your question.  Since you were planning on starting in May, why not wait a month and start in June with the new meds.  Sounds like 24 weeks is pretty iffy with SOC and getting your best shot at SVR.  You only want to do this once if you can help it.  My 2 cents, use the new stuff and do 24 weeks.  I think it's 12 weeks SOC +PI and the remainder 12 weeks with SOC.   Someone correct me if I have that wrong.  Not too certain on that.
Judy
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