Aa
To Much A Good Thing?
You'd think after 36 weeks I'd get it right. Just did my 36th shot and like a dumkoff, didn't even think to make sure I had 180 in the syringe. I just stuck it in and drained the whole thing! So, since I can't back up and try again, what's too much going to do?
There's less in the pre-filled vials than meets the eye, once you get all the bubbles out, etc. In fact, I doubt if there's more than a tinge over 180 in those vials anyway, if that. I always injected the entire pre-filled Pegasys vial as did many here. Not to worry.
-- Jim
-- Jim
To clarify, i was talking about the pegasys pre-filled syringe. After re-reading your post not sure exactly what you injected from, but as FlGuy says, many of us have done 360, so probably not to worry.
Thanks guys. Not that there was anything I could have done about it anyway but at least I have peace of mind, knowing I'm not going to have some kind of side effect (LOL)! It was the prefilled Pegasays 180. Web52, Geno 1a also. I'll try not to slow down and give you that chance to catch up. Just ordered my last three month supply. Good luck!
If it's a pre-filled, just inject the entire vial each time. I also thought I was getting some "extra" but if you look real closely after you get out all the bubbles, etc, and "squirt" that drop or two to get the air out, the vial only holds 180.
-- Jim
-- Jim
im right behind you, in 1 hour and 45 minutes i will do number 32. only 16 left! not that i'm counting, but july 6 is my last shot :-) im on pegasus prefilled 180, i have always just stuck it in my belly below the waiste after selecting the spot. think i looked once or twice, but i just don't bother with checking, getting air out or anything else. i do inject slowly though to make sure i don't get any backup. im a 1a and have been und since day 22 (i am also in the vertex study).
We had instances of what could be the same thing in the Vertex Prove 1 trial.
The assay is done on Roche Taqman, which gives results as quantified result [eg 240 IU/mL] or a UND result <30 IU/mL no HCV RNA detected.
Some of us got a weird result, which was 29 IU/mL. The obvious question was, " how the he!! can a test that reads down to 30 IU/mL give a result of 29 IU/mL??" Turns out that Taqman, and other current sensitive assays, does two types of test:
- a qualitative test, that detects HCV RNA as present ot not present
- a quantitative test that counts the HCV RNA as reports xx IU/mL
The mystery 29IU/mL happens when the qualitative test shows that some HCV RNA is present in the sample, but not enough to be counted by the quantitative test. It tell us that some amount less that 30IU/mL was detected.
We've seen cases where a fellow Prove 1 poster had several samples taken over a single day. All were UND [<30 IU/mL no HCV RNA detected], but one was <29 IU/mL. The 29 sample in this case may have been a false positive, or may have been a really low amount of HCV RNA in a single sample.
It was pretty confusing for us too, so you are not alone :-)
The assay is done on Roche Taqman, which gives results as quantified result [eg 240 IU/mL] or a UND result <30 IU/mL no HCV RNA detected.
Some of us got a weird result, which was 29 IU/mL. The obvious question was, " how the he!! can a test that reads down to 30 IU/mL give a result of 29 IU/mL??" Turns out that Taqman, and other current sensitive assays, does two types of test:
- a qualitative test, that detects HCV RNA as present ot not present
- a quantitative test that counts the HCV RNA as reports xx IU/mL
The mystery 29IU/mL happens when the qualitative test shows that some HCV RNA is present in the sample, but not enough to be counted by the quantitative test. It tell us that some amount less that 30IU/mL was detected.
We've seen cases where a fellow Prove 1 poster had several samples taken over a single day. All were UND [<30 IU/mL no HCV RNA detected], but one was <29 IU/mL. The 29 sample in this case may have been a false positive, or may have been a really low amount of HCV RNA in a single sample.
It was pretty confusing for us too, so you are not alone :-)
No sure how much you injected. Probably won't be a poblem. I've done 2 180's (pegasys) at the same time (different abdomen spots) and wasn't that bad for sx. I've estimated that the peg sx for 360 is only about 25% worse than a single 180 and most of that on day2 shake, rattle and roll..
Ignore all that - dropped the right answer in the wrong thread!
Danke Schon jmjm. I remember now, reading on another thread a few months back (maybe yours), that they were injecting it all as well. And you're right, the residual is insignificant. I should've been doing it all along. Waste not, want not.
It's been known to happen that folks will intentionally get the air bubble up to the plunger so the air forces the last of the peg out. My guess is that the graduated lines account for that which would be left in the area below the plunger, and so the residual air pushes that extra bit down the chute. Definitely an off label injection technique.
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