Rising Alt, Ast on Tx

[Tippyclubb]

After 2 weeks of being on tx my ast, alt dropped into the low 20's.  Last blood test they rose into the high 30's, which is still in normal range, but I'm not doing anything different and just wonder why they are rising.  I don't think these numbers have anything to do with vl, do they?

[HectorSF]

I just wanted to reassure you. I think your AST/ALT will continue to vary quite a bit during treatment. Even for people not treating the levels can vary due to many external factors.
The the real prize is your viral load and its response to treatment. Let us know when you get your 4 week HCV RNA results.

All the best!
Hang in there.
Hectorsf

[Bill1954]

No, there doesn’t appear to be any direct correlation between viral load and liver enzymes; at least none that I’m aware of. I’ve heard different explanations for why enzymes might rise during treatment, but none of it makes much difference in terms of SVR. May folks have reported elevated AST/ALT during treatment; one that comes to mind readily was FLGuy- you might want to flag him down and ask him about his experience. He’s SVR now, so try not to worry about it too much—

Bill