undetected VL week 4

[pcds]

Very happy, this will help me get through the misery they call treatment.  Started neupogin tomorrow and procrit shortly thereafter.  They halved my peg this past friday to 90.  Hope to increase it this coming friday.  My riba is still reduced from 1000 to 800. Mayo doc says if you do 80% of dosing you have same chance of SVR at 100%.  

I had a really tough week end.  Thought I couldn't go on.  But like my buddy Spectra says, don't get caught up in the moment, because it will change.  He was right.  Today I went to work, it was better and then this news.  Sure helps.

[Wildorchid1121]

That is definitely awesome news, congratulations.

[roostermom]

Today is week 9 on Incevik and I am feeling awful. But -- undetected so worth it. Just started procrit yesterday at 9.1. Every bone in my body hurts. Last time I treated I was on neopogen and I assumed that was what was causing the bone pain. My doc did not lower peg, but has cut the ribo from 800 to 400 for the first week of procrit.

Does any one know if the procrit makes you feel better, or does it just stop the hemoglobin from dropping further?

[spectda]

It's all about timing. Reducing anything before und is not a good idea and personally and in my opinion should be an absolute last resort.

Judy you know my take on it, Since you don't have critical HGB (10.1) and your ANC is .81 and your getting neup and procrit this week I really don't understand why they are reducing you, Maybe the Riba while you get the procrit, but the interferon in half before they even had your pcr result, WTF?

Even if it's mayo clinic some other respected hepatologists are much more aggressive then them and I believe (not positive) that the in the telaprevir studies does reduction for ANC was .5.  You want to make the very likely 24 weeks count. Not getting enough riba could very well effect getting to und or the chance of relapse. They don't have 100% SVR, so I would do all I could to take the full dose personally.
-Dave

[elpasolady]

"The riba and peg can be reduced.......... Not the same for the PI though"

Thanks, Can-do, I am well aware of this fact.  Pcds said in her post that the drugs being reduced were only the INF and RIBA, not the PI.  That news can be encouraging for those that are getting the SOC drugs reduced.

[working dog]

good news.....my third through 5 week were so tough...now in week 8 i'm fine....i have sx but nothing i can't deal with.....billy

[scoleman]

Wonderful, wonderful news.

Sherry