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CERTAIN PAIN MEDS DON'T WORK...IS IT MS RELATED?

Hi Everyone,

My issue today is....Has anyone dxed with ms ever found that there are certain meds that do not work right for them? For instance, I was given Vicodin after major surgery for pain, because percacet upsets my stomach.  The Vicodin did nothing, nadda, didn't make me drowsey,didn't do anything for the pain, felt like I took nothing.  The Dr had also given me valium for a throid biopsy, same thing, did nothing.  Had another biopsy same area, told the Dr that the valium did nothing, so he gave me Ativan, same thing did nothing.  Now I am being told, after an episode of ON, and a myriad of other symptoms, that I probably have ms(othamalogist dx), but he said I need a final dx from the ms specialist or neuro.  My question,.....  Does anyone here find that they have the same problems with their pain meds, and do you feel that this may be linked to ms?  I also noticed that my nervous system is very sensitive, to loud noise, light, etc, and I have alot of nerve pain and discomfort.  I was also dx with Lherimettes Sign. Do you think they are connected to ms?  Tell me what ya think guys.  Thanks!  Hugs to everyone, hope your day was a good one!   Sandie
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739070 tn?1338603402
PS to the my above post. Check out the Health page entitled Paresthesias , Things that go Buzz in the Night.
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739070 tn?1338603402
I'm not sure MS would necessarily affect meds used to relax people. For instance, my son , who undergone multiple medical procedures has the same lack of response to Versed, Ativan and Valium as you do. His docs told us that's just the way his body reacts.

Another point, which may or may not be related to your situation is that redheads (of which I fit the bill) metabolize medications differently than others. I had a pain management doc tell me this (he was redheaded too) and said it takes up to 1/3 more pain medicine in redheads to achieve the same effect. That would explain why my LP was painless when he did it and when his partner (non-redhead ) did the blood patch, I swear the man didn't use ANY lidocaine to numb the area. I have also read the literature which states that the gene causing the red-hair is linking to enzymes related to drug metabolism.

Neuropathic  pain is pain that has it's origins in injured nerve pathwyas versus the pain encountered due to trauma or surgery. I am not sure if it's related to the MS. Perhaps someone else can chime in here and answer that for you.

Good luck and feel better!
Ren
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611606 tn?1315517767
Hi there, the only medication that touches any of my pain is morphine... I have very deep bone pain 24/7, but nothing helps with the bladder or rectum pain which is often at 11or 12 on the 1-10 scale.  I have been told by four different doctors, that they know of nothing that will relief the pain caused by this bundle of nerves that lie between the lower bladder and colon...
I can't use a lot of different drugs because of bad reactons...
My Thoughts and Prayers go out for you, hang in there and Don't give up....
{{{{~!~}}}}
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Avatar universal
Hey rendean

What's considered neuropathic pain. Would pain after belly surgery be this kind of pain?Would this be why meds used to relax a person be in this category?  So does this mean that it could be related to MS?  Thanks for your answers.  
Thanks,  I am working toward feeling better hopefully, you too!  Sandie
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739070 tn?1338603402

If your pain is neuropathic in nature, "regular" pain meds will not work due to the  different pathways that cause this pain and the damage to the nervous system. That's why a lot of the meds prescribed for neuropathic pain are off-label seizure meds, etc. The Health pages (found at the top right of this page under the yellow icon) can explain this better.

Hope you find your answers and feel better soon.

Ren
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