Can high levels of antibodies on thyroidism relate to cervical dysplasia?

[cheli55]

Hi. I've been having my thyroid checked a few years not due to enlargement on the right wing and nodules on the left wing...TSH levels are normal and nodules appear to be benign... my diagnosis was hashimoto's and My endocrionologist says I'm closed to thyroid failure (hypothyroidism)...My antibodies are very high...Acording to My Specialist, I'm supposed to be at a level of about 30 and tests have been showing levels between 700 to 900...
I'm not taking any medication yet due to normal TSH levels...

I'm currently going under treatment for cervical dysplasia and eventhough I have always have had normal paps.. all of a sudden I get an abnormal pap with high levels of dysplasia...CIN III and still waiting to check for severe cervical cancer.

MY QUESTIONS:

1. Could my fast progress on dysplasia be the cause of high antibodies on TSH(thyroid)????
2. Could my immune system be weak????

Please reply ASAP... Thank you

[Red_Star]

"There is a high (approx 40%) prevalence of B12 deficiency in hypothyroid patients. Traditional symptoms are not a good guide to determining presence of B12 deficiency. Screening for vitamin B12 levels should be undertaken in all hypothyroid patients, irrespective of their thyroid antibody status."

Vitamin B12 deficiency common in primary hypothyroidism.  J Pak Med Assoc. 2008 May;58(5):258-61.


"Low vitamin B12 serum levels were significantly statistically associated with increased low-grade (OR = 4.08; 95% CI = 1.41-11.79; p < 0.05) and increased high-grade cervical dysplasia risk (OR = 3.53; 95% CI = 1.24-10.04; p< 0.05) for the highest vs lowest quartiles of serum vitamin B12. This study indicated a relationship between low vitamin B12 status and increased risk of cervical cancer."

Vitamin B12 status of Thai women with neoplasia of the cervix uteri. Southeast Asian J Trop Med Public Health. 2006;37 Suppl 3:178-83.

[lmmgamomma]

I had this also i have hashimoto's. My discharge was due to debris from a cyst i was told. I off & on have pain in same breast and they say it is a recurring  cyst.  I have read somewhere that it is related i will have to find the article.

[cheli55]

Hi...6 months ago I had my first mammogram due some bloody discharge on right breast.. they didn't find anything on mammo or ultrasound.... My doctor who happends to be a breast surgeon, just gave me some antibiotics to clear it up... he said it might just be an infection...that maybe i hurt myself and can't recall (inpact to the breast or some sort) anyway he recommended a follow up for another mammor 6 months after that.. Yesterday I went to my doc to get the referral for the mammo since it's been 6 months, and he recommended to wait another six months cuz it's not good to be getting many x-rays and the breasts feel normal...I asked about the high levels of antibodies due to thyroid disease...I too was diagnosed with Hashimoto's disease...goiter and nodules found...doctor said it had nothing to do with it...but I will ask my endocronologist about this... my app is in May....

About the cervical problem he said that the bloody discharge from the nipple could have been some kind of hormonal inbalance (what causes this???) and the hormonal inbalance could have affected my mild dysplasia and advanced so fast to severe dysplasia which is not CIN III... I looked up CIN III and it means Carcinoma-in-situ (cancer in place)  I guess cervical cancer stage 0 (beginner)... I go monday for pre-op to OBGYN for my cold-cone biopsy surgery.... I definitely have many questions for her about this!!!!  Thanks for your comment... keep in touch...

[redheadaussie]

My mother had Cervical cancer stage 3 before she found out she had thyroid issues. I had a pap test done and I have high levels of inflammatory responses..meaning no known obvious reason other than the body may be fighting an infection.
I have Hashimoto's disease..my anti-body levels were 1442  5 months AFTER I had my left lobe removed.
I think there could be a link between the two. My teeth have suffered badly too, recurrent abscesses with no obvious point of entry for infection.
  I truly believe the body, has many issues with immunity. Once you get diagnosed for one thing, it does not mean the same thing is not impacting elsewhere...they just label it a different thing!

[cheli55]

ok thanks:-))

[laura1967]

I personally have never read anywhere where the two have been related. BUT the immune system is definately where the weakness lays.