I've been taking thyroxin for 5 years. I'm 58. I love to be physically active but now i have mild leg pain, hip pain and shoulder pain. Sometimess i have elbow, knee or other pain.It only hurts when I work out, or walk for more than an hour. I went to a pain dr who gave me some blood tests. My free T3 is 2.o, my free T4 is .73 and my tsh is .194. In addition i have many typical low thyroid symptoms. Depression, memory and other congnitive problems, low energy, splitting nails, dry skin. My d3 total is 41.6 and my crp high sensitivity is .8 mg/L. My neurologist says that I don't have early onset alzheimer;s. I'm also taking anti depressants.