Don't understand test results

[bnincongo]

I don't understand my thyroid test results.  My doctor hasn't called yet for a follow up.

I had at TSH of 4.87 last June.  I wasn't treated for hypo.

Last Thurs my results were:
TSH 0.06
TSI 189
Thyrogolbulin AB 26
Anti-TPO Antibody 89
Free T4 1.4

My symptoms are hypo.  Sometimes I have a few hyper symptoms.  Can I be both?

Thanks for any help.

Linda

[GravesLady]

Did they do a F/T-3, which is warranted with a low TSH.

Some people are hypo before going full blown hyper and some are hyper before going full blown  hypo.

Hypo and hyper share some of the same symptoms, so levels are the ruling factor.

I would repeat test from the same Lab, with all three levels 6 weeks after the above test to see if they correlate wit each other to rule out any error.

Both antibodies above are seen in both Graves', Hashi, other autoimmune conditions and people without thyroid disease.  There are more specific antibodies for Graves' and Hashi.

[Letterer]

What other antibodies are you referring to? I thought TPO Ab and Tg Ab were the two that were commonly tested for to determine AITD, I don't recall reading about any others used as more specific markers.

Thanks...

[bnincongo]

They did a free t4 test that was in the normal range but not a free T3.  I'm not sure why.  I know so little about all this.  So I have antibodies for both Graves and Hashi?  Do the numbers show I'm more likely to have one over the other?  I think I have many more hypo symptoms than hyper.  Fatigue, constipation, cold hands and feet, low body temp, depression...

Thanks....

[GravesLady]

I see they did the TSI which does indicate Graves', but levels must relate to Graves'.  Your low FT-4 is throwing me off because it should be high in Graves'.

Thyrogolbulin AB  and Anti-TPO Antibody are seen in Graves' and Hashi but it doesn't mean you are Hashi/Graves' because they are also seen in other autoimmune conditions and people without thyroid disease.  Therefore thyroid levels are the prevailing diagnose for autoimmune.
For Hashi they should have done TRAB - TSH receptor antibodies: Blocking TSH receptor antibodies
along with thyroid levels.

Your symptoms are not exclusive to thyroid only nor hypothyroid. I am hyper/Graves' and I have or had all the above mentioned symptoms.

I still suggest retesting all three thyroid levels.

[GravesLady]

Graves'
TRAB - TSH receptor antibodies: TSI  thyroid stimulating immunoglobulin (antibody).

Hashi
TRAB - TSH receptor antibodies:  Blocking TSH receptor antibodies

Actually it is suggested for all five, TRAB - TSH Receptor Abs: TSI (stimulating), blocking, and binding, as well as the anti-TPO (thyroid peroxidase) and the anti-thyroglobulin, be tested because some people have antibodies for both Hashimotos and Graves. However they cannot be both hypo and hyper at the same time, but one set of antibodies might predominate at one point in time and  months later the other set could take over, which can makes things much more complicated.
Also, people who have high levels of both stimulating and blocking TRAb have a higher risk for TED  (Thyroid Eye Disease).

[bnincongo]

Thanks for the info!  Let me ask if I understand this correctly....

There are 2 tests that were not done which might give more info...
TRAB-TSH receptor and TSH blocking.  Or is this just one test?

So even though I have these antibodies, it could mean there is another autoimmune problem and I don't have a problem with my thyroid?

Maybe I had the hypo set take over in June and now the Hyper set of antibodies has taken over?

Should I get my eyes tested?  (Thyroid eye disease?)

Thanks again,

Linda

[GravesLady]

This is one test - Out of the TRAB-TSH receptor, you'd want the Blocking TSH receptor antibodies done for Hashi and/or TSI  thyroid stimulating immunoglobulin (antibody) for Graves'.

Thyroid levels (TSH and both FTs) relates if you have a thyroid problem, not the antibodies.  Antibodies just CONFIRM what type of thyroid condition thyroid levels are relating to. People with normal thyroids have antibodies, that is just nature, or they do appear in other autoimmune condition, but not mean you have a autoimmune condition.

Levels and specific antibodies can only relate if you were hypo turned hyper.  I wouldn't assume it as fact with out test relating it.

If you are having eye problems it wouldn't hurt to have them checked out,
especially if you have both stimulating immunoglobulin antibody and blocking TSH receptor antibody, which relates to a possible TED.

[GravesLady]

bump too top