I have read from several sources that either high or low cortisol can adversely affect hypothyroid patients. You can get some good info from this link.
http://www.hormonerestoration.com/Cortisol.html
With Free T3 level being so low, I'd suggest 5 mcg., split in half, for the morning and early afternoon dose.
Do you have any knowledge/information on the relationship between cortisol and hypothyroidism, as well?
Also -- if I attempted to up my Cytomel, is it best to go by 2.5 mcg or 5 is not too big of a jump? Of course I'll notify my physician, but I'm feeling a bit like I need to take matters into my own hands to feel better.
Doctor said he only wants to change one thing at a time, then re-examine in 4 weeks. I suppose it's somewhat conservative, but I am okay with that. Ideally, I'd like to be on the least amount of medicine plausible.
Also, maybe I am crazy, but I feel better already. Not perfect -- but last night I couldn't even walk from my couch to my bedroom, and I have a ridiculously tiny house, because of joint pain. Today I walked 4 miles, with minimal joint pain. :)
I'd like to say right away, but i"d be lying. Your Free T3 level is so low that I don't expect that 5 mcg is going to do very much for you, except get you moving in the right direction. So, I would make sure the doctor knows that the full effect on serum Free T3 levels will be evident in less than a week. So, I'd plan on pushing for follow-up tests as soon after that as you can convince him to do so.
With your Free T4 being so low, why is the doctor reluctant to address that? No reason why you can't take both T4 and T3.
Also, don't forget to get tested for Vitamin D and B12 at first opportunity.
I got Cytomel!! Hurray! My FT3 had fallen off the charts and FT4 had dropped even lower, too. He doesn't want to up the Synthroid yet, but instead have me retest in 4 weeks. I'm starting on 5mcg Cytomel. :) When can I expect to feel a bit better?
I was diagnosed Hashi's, yes. Except the only antibodies that came back out of range were TBII. The others were elevated, but not out of the lab range. The closest to being out of range was actually TSI at 120%. However, I agree with you, that I clearly need thyroid medication when my Frees are in the gutter.
If he tries to take away my medicine, I'll find a new doctor. I'm questioning him now, because I asked if iron overload could have damaged the thyroid or pituitary gland, and he said no. From my, albeit limited, researching on the subject, I know that to be untrue. It does/can affect thyroid and pituitary. So, I guess I will see what the hematologist has to say in a few weeks.
I wish he would just treat the endocrine problems and not speculate on anything else, however. Because I really don't feel like being miserable for another 2 weeks. :(
Interpretation of test results
Question:
Could someone please comment on these test results? Ferritin, Serum: 45 -- range 15-150. Iron Bind Cap. (TIBC): 422 -- range 250-450. Iron Saturation: 55% -- range 15-55%. Iron, Serum: 232 H -- range 35-155. UIBC: 190 -- range 150-375. [Lab Tests Online Question referred from: /understanding/analytes/ferritin/tab/faq]
Answer:
Response:
Thank you for contacting the American Society for Clinical Laboratory Science (ASCLS). We are a team of laboratory professionals who volunteer our time and expertise to assist consumers in understanding laboratory tests and results. We try to answer questions within 72 hours, but due to the large volume, we occasionally need more time. An Iron Saturation of 55% is borderline high. All of your other values are normal. You did not give your age or gender which can have a bearing on interpretation of these test results. Also, iron studies should be done on a fasting early morning specimen and you should be off of any iron supplements for at least a week. If you complied with the above, then I would suggest having the tests repeated just to make sure that the saturation level is correct. If it stays the same (i.e. increased or borderline high), depending on your age and gender, you may want to consider some follow-up testing for the condition known as hemochromatosis, or at the very least, repeat the iron studies in six months to see if the % saturation is staying the same or increasing.