I had been taking 75mg of levelthyroxine for several months, then started to feel tired, after a blood test my dose was increased to 100mg. After a while I started to have heart palputations and feeling very anxious, I was advised to take 75mg one day and 100 the next. I felt all over the place, one day ok and then feeling tired. My doctor agreed that I could cut up the tablets so I could take the same amount each day. I am still feeling very anxious even after 4 weeks, so I am now on medication for anxiety. My question is, why would 25mg made such a difference to how I feel, I would have thought there would be a leaway between amount of doses.