My mother was put on Levothyroxine several years ago..and it was controlling her Hypothyroidism well. Just last year her Dr double her dosage because Mom's numbers had increased some (like I said SOME). Instead of gradually increasing it gradually...Long story short, My mother has developed high systolic blood pressure (the other number is in normal range) and has very frequent Migraines. The doctor put her on a betta blocker which has done nothing for her. My mother has talked to her Dr about it, the Dr has lowered her dosage some, but I still have a feeling there is a connection. My mother had also complained about feeling on edge or like she couldn't sit still. She has always been a very active person, never been over-weight and I am wondering if, at 118# her dosage is just too high. Would like to know what others think??? She has gone thru many tests lately to rule out other things and the Dr is still perplexed.