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Graves Disease?

Hello. I am 40 years of age and16 weeks pregnant. 4 weeks ago, I had some thyroid function tests come back indicating hyperthyroidism.

Free T4 27.4    (10.0-19.0)
TSH      < 0.03 ( 0.5-4.0)
Free T3 12.5     ( 3.5-6.5)


I also had antibody tests under taken.

Anti-thyroglobulin: 263 kIU/L  ( 1.5)

My anti-thyroid peroxidase were within normal limits.

I was placed on 300mg PTU daily and some of my symptoms (eg- tachycardia and sweating) have reduced.( I have been feeling quite unwell for around 2 years and, around 18 months ago, my GP wanted to start me on anti-depressants for anxiety and nervousness. I didn't feel right about taking them, however, so the prescription was never filled.)

Do the above results indicate Graves disease? Also, are the TSH receptor and thyroglobulin anti-body titers a cause for concern regarding possible problems for my baby, even if things settle down, T4,T3 wise in the last half of pregnancy?

Thank you in advance, quietly concerned mummy.
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231441 tn?1333892766
Hi,

they need to medicate the hyperthyroid very carefully during pregnancy to avoid becoming hypothryoid.  It will be a fine balancing act.  Please make sure the doctor tests frequently (probably every 2 weeks).

I can't answer on the antibodies effect on your baby.  But antibodies are quite large molecules and maybe they don't cross the placenta.

Best wishes.
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Avatar universal
Not sure why it keeps cutting out part of the post. Normal range for anti-thyroglobulin =  1.5 IU/L. :)
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Avatar universal
Sorry, I meant  Anti-thyroglobulin:  263 kIU/L (  1.5 IU/L)
Helpful - 0
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