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314532 tn?1206415109

Still tired and frustrated

So I have been seeing my endo since May 2012. I have Hashimoto. my endo had me on levothyroxine .025 5 days a week and .050 2 days a week. Everything had been going well. Almost all symptoms were relieved until December. I thought that maybe I was feeling exhausted again because of being busy with the holidays but it was actually because the meds had stopped working. My TSH just about tripled in 6 weeks. He switched me to Synthroid and increased my dose to .025 3 days a week and .050 4 days a week. I have been on this dose for 6 weeks now.  While I don't have my most recent labs back I can tell you that my symptoms have not approved. I will see my endo next Thursday and get my labs then. I will post them once I have them. My question is...is it normal for meds to just stop working and TSH to triple is 6 weeks? Does anyone have suggestions for combatting the exhaustion?mi am so tired that sometimes I can't even concentrate! It's so frustrating.
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314532 tn?1206415109
I don't understand what you mean when you say I seem to be more hyper sensitive to t4 rather than t3. Additionally, before I even started treatment my endo did adrenal testing which came back within range. Could it be different now? Is that something that could change within less than a years time?  I think the sweating may be a side effect of the T3. While i had the sweats before starting treatment they had pretty much gone away once my the was around 1.2 until about December when my TSH just about tripled. We are still working on lowering my TSH again and thus the addition of the T3. I am hoping that once I adjust and get my TSH lowered again the sweats will go away again. My doctor has not armour or anything like that with me. Does it work better? What is the difference? I have an appointment coming up in the beginning of April so maybe I could discuss it with him.
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314532 tn?1206415109
I am taking 10mcg twice a day.
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Avatar universal
I am wondering more about adrenals (cortisol) related to the night sweats.  As we know cortisol fluctuates significantly throughout the day.  This could be some reaction to adrenal fatigue and the adrenals trying to get balanced out with the now introduction to new medication and new dosage levels.

These hormone things are complicated. And it is like dropping a stone into the center of a pail of water. The ripples not only go outward in all directions, but they also reflect back from the walls of the pail and keep doing that. But over time the ripples get smaller and smaller and go away.

Are you experiencing the first and thus largest waves of this ripple affecting all the other hormones and adrenals and getting weird reflections back?

Just trying to explain a possibility.

Also worry and stress has a significant factor on the creation of reverse T3 and thus some effect on conversion.  So the more you worry the more that could contribute to the conversion issue.  On the other hand, that would tend to cause you to be more Hypo then your labs would otherwise indicate, not Hyper like you seem to be experiencing.

It is interesting that you seem more hyper sensitive to T4 rather than the T3. The exact opposite that most people experience. But that is why they call us unique "individuals".  Because not everyone reacts the same.

With your sensitivity, I was wondering if any thought has been given to try Armour or another natural dissected thyroid med?  I wouldn't necessarily recommend the switch now until you give a little more time to try to sort it out on the track you are on now. But if that doesn't work out, that is another avenue to  try.
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Avatar universal
It's probably the T3 doing that.  There's an adjustment period when staring it.  Please refresh my memory...how much are you taking and do you split your dose?
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314532 tn?1206415109
I started the T3 meds almost two weeks ago and I was wondering if anyone else that is taking T3 meds has heating regulating issues?  Prior to being on meds for my thyroid I use to have awful night sweats that seemed to get better once my meds kicked in.  However, since I started the T3 not only am I having night sweats again but I am having random hot flashes and sweats throughout the day now. Hot flash and sweats so bad that my clothing is damp. Any suggestions?  I also have a call into my doctor but haven't heard anything.  
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Avatar universal
It could be.  Last time I was overmedicated, my endo had advised me to take no meds for three days, then go back to my former dose.  In that three days, most of the symptoms went away, but it was a couple of weeks before I was back to feeling like I did before the increase.

Don't hesitate to check in with your doctor on this.  He might be able to give you something to get you over the rough spots until your thyroid meds get stabilized.
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