TPO level at 30,000

[SophiaMia]

Has anyone had this high of a TPO level?  This is my first test.  I keep reading people's levels at 2,000 or so.  My TSH levels are also elevated, but I'm not sure of the numbers.  I am experiencing Hashi's symptoms, but I'm a little freaked out about the high levels.  I'm waiting for a referral for an endo.  Any advise as to what to ask him or test I should request?  Any advise is well appreciated.

[estrelinha]

Yes, don't worry to much about that, my ENDO told me that he had patients with a very high titer, whish means your autoimmune disease is very active, and you must be carefull with your thyroid levels (to not become very hypothyroid). I would ask for an ultrasound.
TPO antibodies can also cross react with ANA's , if you have an autoimmune disease you can have another, just remember this. I discover that I had a thyroid problem because of my TPO antibodies, I also have positive ANA's, this was last year. I did all possible autoimmune analyses and all came back negative. Now I still have high TPO antibodies, normal thyroid levels and no medication (feel ok), so this Hashi thing didn't go so quick as I expected. Last month my doctor asked again for all autoimmune analyses, just routine (my ANA's are 1: 615).

[SophiaMia]

Thanks for responding.  I am taking thyroid replacement and waiting to see the endo.  The 30,000 number just seemed so high.  I'm a nurse and that number even freaked me out.  Have you ever heard of any so high?

[estrelinha]

Yes looks like Hashi, mine are more then 1000, so I don't know if it's much higher. If your TSH is high with that antibody titer, you should start treatment.