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thyroid labs

I've been on synthorid 88mg for three months due to hypothyroidism.  Had some lab work yesterday and my free t3 was 4.69 pg/ml, my tsh was 0.03uU/ml and my free t4 was .84 ng/dl.  I'm still really tired and have really dry skin.
what does this lab work mean and how come I'm still having symptoms after 3 months of meds.
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Avatar universal
I just looked back at your post from the early part of February and saw that your FT4 went from 0.73 to 0.84.  Your FT3 went from 3.56 to 4.69.  And your TSH went from 1.48 to 0.03.

Your FT4 is still very low in the range.  Your FT3 is now over the top.  And your TSH is very low.

You have tons of FT3 circulating in your blood, yet you still have hypo symptoms.  With FT3 that high, it's very unusual to have hypo symptoms.  Something more complicated has to be going on.  For some reason, the FT3 is not getting to your cells. where it can be used.

RT3 dominance is a possibility, but unlikely due to the very high FT3 level.  Still might be worth checking the RT3 levels since it's the ratio of FT3 to RT3 that's important, and your FT4 is very depleted.

RTH (resistance to thyroid hormone) is another.  In RTH, cells are resistant to T3 until it is in very high concentrations.  This is a genetic anomoly and very rare.

My best guess (and that's exactly what it is) is that you have adrenal fatigue which is not allowing your FT3 to be used by your cells.  Definitely worth checking out.

I hope someone else will pipe in with other ideas.  Very unusual...
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Avatar universal
No I don't know the cause of the hypothyroidism.  I can't get into the endocrinolgist until June.  Antibody testing was negative.  Thyroid u/s was negative.  Reference range for free t4 is 0.70/1.60ng/ml, tsh reference range is 0.40-4.50uU/ml and reference range for free t3 is1.50-4.10.
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Avatar universal
Please provide the reference ranges from your lab report.  These are lab specific and have to come from your own report.  Do you know the cause for your hypo?  Have you ever had antibody testing?
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