if you plan on trying this evening dosage - you shouldn't mix it with the other meds.
i always take my levo at night before i go to sleep. i don t eat anything after 6p. i started doing this after reading so much about the benefits and it really works for me. but i have not taken anything with the levo.. good luck
If you being hypo is the result of an autoimmune disease. I'd stay away from melatonin, it just makes things worse.
I don't know about specific interactions here, but the rule of thumb is to take thyroid meds first thing in the morning on an empty stomach. You should not eat or drink anything but water for a half to one hour after taking meds. You should not take any other meds or supplements with your thyroid meds or for 3-4 hours after.