The rule of thumb with Cytomel or any T3 med is 5-6 hrs after first dose. But, some people also take dose in the morning and dose in the evening. It is really up to you and how you feel. You should wait at least 5-6 hrs after your morning dosage though.
T3 meds don't stay in your system long.
What is most important is how you feel. :)
I was wondering how you are supposed to space it out. My doc told me to take the whole thing in the morning but when I do that I don't feel so great. So, I just decided that 3 would be a good time. I take the first half between 7-8am, when's a good time for the other half?
Many hormonal issues can make you sweat. You should get a good workup of your hormones, estrogen, adrenals, etc...A good way to see if it is Cytomel is to skip your PM dose once and see how you feel. Or maybe take it at noon, rather than three.
:) Tamra