Not to worry. My first TSH was 98 and . . . I'm still here. I have read on this forum of someone up to 600(?) TSH. Seems outrageous, but I think that's what they said. You are on meds for low thyroid and your TSH will start lowering. You won't go into coma. Sorry to hear of all your other troubles, so don't worry about this one. Hang in there and get well.
I have read where people had TSH as high as 400 to 700.
It takes at least 6 weeks before you will hopefully start feeling some results from Synthroid. Cytomel is t3, not t4 and should be taken every 6 to 8 hours to keep an even amount in your system. That means a single dose of cytomel would be taken 3 to 4 time in a 24 hour period. Also might mean having to get up in the middle of the night to take a pill. If you don't, you can get side effects like uppers and downers.
Give your medication time to work. Rome was not built in a day, likewise healing.
As far as Myxedema coma, if you get very lethargic to the point of falling asleep and have a hard time waking up and a fever, go to ER.
GL,
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