I've been having random and varied symptoms for about 2 years now and haven't been able to find an explanation.
Started out with chest pain, seems to come in all forms and locations including my arms.
Initially thought I was having heart problems and I began to have skipped-beat type heart palpitations, which I now know were from anxiety and have since subsided.
I finally went to get this all checked out. First was blood tests, everything came out normal except for Homozygous clotting factor XII deficiency, which is extremely rare (1 in 1000000) and can possibly lead to hypercoagulability.
Had event monitor, several EKGs, Stress test, Echocardiogram, all normal.
right after this began having pain in right calf that spread up right leg and into left leg, has been on and off since then. Also noticed a dry patch on the outside of my left ankle that seems to come and go. Pain does not generally get worse with exercise, did several physical examinations with different doctors, and 2 D-dimers, both low and consistent.