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Complcations Of Vicodin Es

my question is can you develope other health problems as a result of taking Vicodin es for a long period of time like heart failure, constapation, etc..I would like to learn all that I can about this medicine since I have been taking it for a long period of time. I don't want to sound like I'm panicing or bug anyone and I do appreicate all the time and effort you all put into this website and anwsering my questions. I'm wanting to just deal with the pain and stop taking it but at times it can be unbearing pain,Just about all of my teeth are decayed into the gums. I have read that some people take them for the high but it is the funny feeling that makes me panic some times but then I would rather deal with that feeling than be in that kind of pain, but when I take it I'm constantly checking my pulse and heartbeat until the feeling wears off. Is their anyone that has or had panic attacks?? See I use to be scared to take anything [any medicine]for about the last five years because when I went threw the starting of my panic attacks I was put in the hospital, that is how bad they got but then my husband got real sick about a year and half ago and I have to focus on him and taking care of our four children, he is not expected to live another year without a Liver Transplant or that is what the doctor's say anyway,and I have faith that god will not be putting him threw all this suffering just to let him die, so when I went to the dentist that is what he gave me and it worked so I've been taking it every since so that is what I found that would stop this pain until I can afford to go back to the dentist and get all my teeth taken care of becuase now it is very hard for me to go to the hospital in the middle of the night and get a shot that knocks me out for a few days, which scared me half to death .Because when I'm in pain I get very agravated and don't want no one messing with or talking to me and I don't know why I'm that way but I'am. Any way that is why I started taking it in the first place and I wish that I would have never started, if I'd only know then what I know now..Well thank you all for taking the time to read this, I know alot of it does not have to do with the Vicodin[in terms of my husband's illness] but just wanted to explain.Well good luck to all with the battle's with medication's and god bless you all. Bizziebe
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Avatar universal
Their are many types of Opioid receptors and also subtypes of them,there are also ~sites? that one opioid ie(methadone)will bind(influence) that another Opioid ie(Hydrocodone)will not.
One thing that all Opioids have in Common is a resonable binding affinity for "Mu" Opioid receptors(PAIN) and stimulation of the Mesolimbic Dopaminergic VTA-Nucleus Accumbens reward circuit(EUPHORIA-unfortunate).
Methadone is goofing you out because it *(binds more tightly in relative global "Mu" receptor affinity to a sub-type) in the Mesencephalon area(brain stem) concerned with  states of arousal and perception.
So it will make you spacey and drowsy and the Hydrocodone will make you "more" euphoric and alert and actived.
Methadone binds pretty strongly to gastrointestinal Opioid *receptors and is considered superior to morphine for stomach pain.
In fact I ONCE used so much Codeine SO often that instead of an Adrenalin RUSH resulting from fright I would get a Codeine RUSH,I have not bothered looking into the Neurophysiology behind this effect,but am not to surprised as Codeine is stimulant and will cause convulsions as per any stimulant in doses that are large(>300mg single oral dose).
Some Opioids are not very specific at all(Mu)receptor and are more Hallucinogenic than Analgesic,so they are not used much.
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Also,It sounds like you are a Methadone Virgin,in which case you will have exquisite sensitivity,enjoy,while it lasts.
Methadone is ofen used for chronic pain sufferers in Australia,as it is considered qualitatively superior to Morphine for Chronic pain and can be given in a way that gives very stable blood levels,below is very approximate for single oral dose,nb Methadone will accumulate due to long half life.
10mg Methadone is equal to 30mg Morphine
30mg Morphine   "    "   " 50mg Hydrocodone
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Avatar universal
Sir, I can only point out the difference in the two medications.  Vicodin is a short acting medicine with actions similar to codeine. Methadone is a long acting medicine with actions similar to morphine. That is the basic difference. Methadone maintenance is about finding an adequate dose that stops all opiate cravings
and withdrawals. MMT is not about producing a high. Higher doses are needed some times to achieve this need. Pill addicts require doses in the 60-80 mg range to stop all cravings
and withdrawals. MMT is about being comfortable for 24 hours without cravings and withdrawals. Higher doses are needed to accomplish this feat. The high associated with methadone will rapidly disapate to produce a patient that functions without craving and withdrawals.
Dan...
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Avatar universal
What you say is correct,what do you think about bizziebe`s original question?.
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Avatar universal
From reading your post here and the one below, I would say that you need to be treated for panic and anxiety.  My own wife has similar problems with narcotics and usually refuses them in favor of Xanax.  She has cancer related pain and has been prescribed mega-doses of Lortab and Vicodin ES.  She rarely uses them out of fear of addiction and the "funny feelings" they give her.  For the life of me, I don't understand it! I'm just the opposite preferring opiates over benzos for pain.  J.B.
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Avatar universal
I'm already getting treated for my panic attacks and anxiety with the medication Xanax, but scared to take it with the vicodin and the same reason I won't take Vicoidin every 4-6 hours as prescribed I don't want to get addicted to none of it and be all messed up, I know a few family member's that are addicted and only take them for the 'high' and that has always scared me. I make sure there is a lot of hours in between the two[VicodinEs, Xanax] if I need to take the Xanax. The whole reason I take the Vicodin is because I don't want to deal with my toothaches because they get so bad,and as I have said I don't have money to go to the dentist at this time, but will soon thank god, then I can stop panicing over all this! Haha.. But I wish I could only use the Xanax but they don't stop my pain..And I think I have done pretty good I've been on them for 4 years now but only take it when I have a panic attack which is maybe 2-3 times a week and sometimes 0 that week, I have learned to control my fear in some ways but sometimes the brain just takes over and I end up taking one if the attack stays with me for hours.. Thanks for your comment and good luck to your wife and you. ps:What is Opiates and Benzos??
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