I've been taking Effexor XR (75mg daily) for about two to three years, and I have resigned to quit cold turkey. I don't like what it's doing to me, I can't afford it (my insurance doesn't cover prescriptions) and my doctor refuses to give me any guidance in the matter and I can't reach her any way, despite repeated attempts. I am aware this is ill advised and that I should be weaned off, but as I said, this is how it will be done. Can anyone offer me any advice?