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SAM-E for anxiety?

I have been told by my doctor that I have GAD and he suggested I take Celexa.  I wanted to try something that didn't have a list of side effects so I looked into SAM-E and decided to give it a try.  I have been using it for the past 10 days and it seems to be working well in a short amount of time.  I have no problem going on Celexa or some other SSRI if that is what it takes to not feel anxiety and all the physical symptoms that go with it, but is it possible for SAM-E to work so quickly?  Could this be a placebo effect?  I am curious what other people have experienced using SAM-E.  I take one pill in the morning and it is 400 mg.  I was thinking about taking one in the morning and one at night, but I want to know what experienced users have done.  
Please list how long you have used it, at what dose, what times of day you take it and what your experience was with it....thanks.
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Avatar universal
I've never used it successfully, but keep in mind that if it works your main problem may be depression, as it's an antidepressant, not an anti-anxiety remedy.  Many people's anxiety is caused by depression, which is why it's so difficult to treat and why CBT so often fails.  As for your question, if it works for you, who cares what others have experienced?  There are natural remedies specifically targeted for anxiety, such as herbal relaxants, taurine, and 5-HTP (which is for both depression and anxiety), but if this is working for you than great.
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3455166 tn?1347507133
Hey there, I haven't used SAM-e, but it does have pretty good benefits.

Apparently, quite a bit of testing has proven it has efficacy in treating both anxiety and also depression, so I would not think this is a placebo effect taking place. To test it, you can go off SAM-e for a week and then monitor how you are feeling emotionally, and if you aren't feeling all that well without taking it, then that would prove its working.

I forgot the specifics of it, but SAM-e has something to do with enabling better release of a certain neurotransmitter, not too sure but it does something like that. Omega-3's can do similar things, some studies suggest that diets high in Omega-3's like fish and seafood, actually may reduce the incidence of depression or depressive states in people.
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Avatar universal
Anyone with experience using sam-e?
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