Hello all, I am new to the site and thought I would give my question a whirl. Hopefully someone has some insight into my problem. Within the last 2 weeks I started tappering off of 75mg Effexor XR, stopped taking my birth control pills, started Metformin for insulin resistance and 150mg Wellbutrin XL. I am doing all of this because my husband and I are trying to have our first child. I suppose it would be best to add that I have taken Effexor XR on and off for the last 5 years, went up and down from 75 to 150. I have a love/hate relationship with this medication. It works better than anything else but coming off makes me a crazy person. Recently I have tappered it as my doctor requested, started the Wellbutrin and Metformin just as I was supposed to.. I was fine for 3-4 days and suddenly I become a nervous wreck, having totally irrational fears of my husband dying, about being hit by a car. Just totally crazy thoughts. I'm wondering is this because all the Effexor was gone or did I basically just send my body into a hormonal tailspin with the switching around within a week? I have always had trouble with depression and anxiety but the anxiety I have felt the last few days is worse. I was thinking maybe I should keep taking the Wellbutrin to make sure it reaches full potential before I wean off the Effexor? Any ideas would be much appreciated!