Reglan caused severe anxiety and depression

[RZ67]

Please help me, my doctors can't seem to.  I started having panic attacks twenty years ago and ever since then I take Imipramine and use Xanax only when I feel panic. I used to think my panic attacks way back then were severe until now.  Now I would say they were moderate.  Two months
ago my GI doctor prescribed Reglan for my IBS/Constipation, and after five weeks I started feeling unusally panicky, depressed and I couldn't find enjoyment in my usual activities. Those symptoms increased every week and pretty soon I couldn't even drive. The medication information I got from the pharmacy listed anxiety as a side effect and said to contact the doctor immediately if you experience depression.  Within the next few days after stopping the Reglan, my anxiety and depression became extreme and I had thoughts of suicide.  I also had a headache for two days and had hot and cold flashes.  I spoke with my psychiatrist and two pharmacists and they all claim that the Reglan is out of my system and not causing the anxiety and depression. I know they are wrong, this is so different! It has now been almost two weeks since I've stopped the medication and I am no better than I was right after I've stopped. My psychiatrist wants to try me on different antidepressants but I am afraid because I've tried many and I had bad reactions to them. I searched my side effects with the medication on the internet and found numerous people that had the exact same symptoms as me for months after stopping Reglan. The FDA website warns doctors about perscribing Reglan to people with a history of anxiety and depression and have reported a suicide from Reglan. I am only looking for reassurance that this will go away and I will get better. Please help.

[hopethishelps345]

i was having a severe migraine and am 16 weeks pregnant- i went to the hospital and they gave me this in my i.v. 5 minutes later i was EXREMELY anxious, felt very panicked and wanted to leave the hospital immediately. i was very restless and couldn't figure out what was wrong with me until i did some research. I found out that the injection version of this is supposed to be administered over a 10 minute period- if given too fast, it is known to cause these feelings i was having. it didnt help my migraine at all. i found out about some of the other potential problems from taking reglan- funny thing- they all say that the doc will only prescribe it to you if the benefit out weighs the risk. it seems to me that throwing up or having gi issues is a better way to live then living with TD which reglan is known to cause. to the person who commented on here earlier with the parkinsons like symptoms- chances are you have drug induced tardive dyskinesia. if you havent heard of it i urge you to look it up as it is strongly related to the use of this drug as well as depression, anxiety, and even suicidal thoughts.

[anonymous680]

http://www3.interscience.wiley.com/cgi-bin/fulltext/118506024/HTMLSTART

"The reason why anxiety symptoms actually emerged in this patient and why they persisted for several weeks after last exposure to metoclopramide is not fully clear. Apart from a conceivable vulnerability of the patient, the gastrointestinal infection being present in both cases when anxiety symptoms emerged, might be of importance. Gastroenteritis can lead to a secretion of cytokines as part of the immune response.Cytokines in turn have been suggested to be mediators of psychiatric conditions such as depression or anxiety."

Maybe you have an undiagnosed chronic gastrointestinal infection that the Reglan stirred up? Sounds reasonable to me. Find a supportive gastro doctor if yours doesn't want to listen.

[mralbostyle]

Same thing hapend to me too but mine is much worse.Never head a history of depression or anxiety but as soon as i started reglan everything came downhill.First symtome was a burning sensation on my neck and terrible muscle tightness.Then after 2 days the depression and anxiety started to kick in.Than latter maby after a week i started to experience parkinsons like symtomes.I quit the medicine 2 weeks later but i guess it was to late.Now without writing to much after 78 000$ spend  and a year later i still have the same symtomes.Been to best  clinics in us (mayo,cleveland,uvm) been to every kind o doc neuromuscular,movement disorder ,headache neurolog) and done almost every test starting with(almost 7 mri,spine lap tab,ssep,and almost every lab test too) been to chiropractor and physical therapy and yet my symtomes wont go away specially the muscle tightness in my neck ,headache and parkinsons like symtomes and the worse thing is i still dont have a diagnose.Now i am just waiting for a miracle so i can be my old self again.Please when ever read this consider a second thought before u take that medicine.IT JUST MIGHT DESTROY UR LIFE.