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Possible diagnosis of Primary Biliary Cirrhosis, need information.
I am currently seeing a Hepatologist and she has ordered a liver biopsy to confirm Primary Biliary Cirrhosis. My lab results are: BUN/Creatinine Ratio is 33 (High), Alkaline Phosphatase, S 137 (High), AST (SGOT) 45 (High), ALT (SGPT) 116 (High), GGT 314 (High), ANA Screen, IFA Positive, Mitochondrial AB Screen Positive, Mitochondrial AB Titer 1:160, Non-Reactive for Hepatitis B
I was also ordered to have an MRI abdomen with and without contrast MRCP for evaluation of bile ducts.
Is the liver biopsy necessary for a diagnosis?
The Hepatologist told me that my levels are only mildly elevated, is this accurate?
Please help!
I was also ordered to have an MRI abdomen with and without contrast MRCP for evaluation of bile ducts.
Is the liver biopsy necessary for a diagnosis?
The Hepatologist told me that my levels are only mildly elevated, is this accurate?
Please help!
Thank you so much for your reply. One final question.... Can someone who tests positive to the antimicrobial antibodies not have primary biliary cirrhosis?
My doctor mentioned that sometimes with fatty liver the blood work will result in a false positive for PBC. I recently had blood work done for a possible overlap with autoimmune hepatitis, but that was negative.
My doctor mentioned that sometimes with fatty liver the blood work will result in a false positive for PBC. I recently had blood work done for a possible overlap with autoimmune hepatitis, but that was negative.
MEDICAL PROFESSIONAL
Hi!
I am sorry to hear about your medical problems. Yes, the levels are not very high but since you have positive antimicrobial antibodies, chances of an autoimmune process such as primary biliary cirrhosis are high. Liver biopsy is the only confirmatory test. However, since other tests are suspicious of PBC, your doctor can start you on Ursodeoxycholic acid and see if you are responding to it. Also, eat healthy, take anti-oxidant rich food, exercise and drink water. Please consult your doctor regarding this. Take care!
The medical advice given should not be considered a substitute for medical care provided by a doctor who can examine you. The advice may not be completely correct for you as the doctor cannot examine you and does not know your complete medical history. Hence this reply to your post should only be considered as a guiding line and you must consult your doctor at the earliest for your medical problem.
I am sorry to hear about your medical problems. Yes, the levels are not very high but since you have positive antimicrobial antibodies, chances of an autoimmune process such as primary biliary cirrhosis are high. Liver biopsy is the only confirmatory test. However, since other tests are suspicious of PBC, your doctor can start you on Ursodeoxycholic acid and see if you are responding to it. Also, eat healthy, take anti-oxidant rich food, exercise and drink water. Please consult your doctor regarding this. Take care!
The medical advice given should not be considered a substitute for medical care provided by a doctor who can examine you. The advice may not be completely correct for you as the doctor cannot examine you and does not know your complete medical history. Hence this reply to your post should only be considered as a guiding line and you must consult your doctor at the earliest for your medical problem.
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