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Invasive Ductal carcinoma of Left b
Hi everyone!
I am new here and jsut got diagnosed with Invasive Ductal Carcinoma, No special type,grade 3 of my left breast After having 2 core biopsies for 3 tumours, my GP gave me the news yesterday.
My diagnoses says estrogen receptors and progesterone receptors are both negative. HER-2NEU analysis is unconclusive for HER-2NEU overexpression
I have no evidence of lymphovascular space invasion or DCIS. This is for tumour #1. They did not do a core biopsy on tumur #2.
#3 tumours shows focal poliferative breast disease.
Differentiation score is 3/3, nuclear pleomorphism is moderate to severe scoring 3/3, mitotic activity is focally brisk scoring 3/3, another area shows a possible area of ducal carcinoma in situ, solid type, high nuclear grade scoring 3/3.
It also shows florid epithelial hyperplasia.
So next step is bilateral MRI for staging and referral to surgeon.
My question is what type of surgery is required, mascetomy? because of multiiple tumours, radiation or chemo.
I also had a resection of my colon 6 years ago for neuroendocrine carcinoma of my terminal ileum.
I also was diagnosed with remitting/relasping MS in 1994. I turned 57 in July.
Any info or comments are appreciated. I live in BC, Canada.
Thank you
Kindly
Diana
I am new here and jsut got diagnosed with Invasive Ductal Carcinoma, No special type,grade 3 of my left breast After having 2 core biopsies for 3 tumours, my GP gave me the news yesterday.
My diagnoses says estrogen receptors and progesterone receptors are both negative. HER-2NEU analysis is unconclusive for HER-2NEU overexpression
I have no evidence of lymphovascular space invasion or DCIS. This is for tumour #1. They did not do a core biopsy on tumur #2.
#3 tumours shows focal poliferative breast disease.
Differentiation score is 3/3, nuclear pleomorphism is moderate to severe scoring 3/3, mitotic activity is focally brisk scoring 3/3, another area shows a possible area of ducal carcinoma in situ, solid type, high nuclear grade scoring 3/3.
It also shows florid epithelial hyperplasia.
So next step is bilateral MRI for staging and referral to surgeon.
My question is what type of surgery is required, mascetomy? because of multiiple tumours, radiation or chemo.
I also had a resection of my colon 6 years ago for neuroendocrine carcinoma of my terminal ileum.
I also was diagnosed with remitting/relasping MS in 1994. I turned 57 in July.
Any info or comments are appreciated. I live in BC, Canada.
Thank you
Kindly
Diana
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I am sorry that you are having to deal with a new cancer dx, this time of breast cancer.
Regarding your question of what type of surgery and what other tx is required, members of your tx team, who will have available all of your images (including those from the upcoming MRI), your full path report from your biosies, other test results,and any relevant medical hx as well as your current medical status, will be in the best position to make recommendations for your particular case.
Meanwhile, a few thoughts about what may factor into that decision:
1. Your information did not give the size of the tumor which was labeled IDC. With BC staging, "size matters," and that may influence the type of surgery recommended. Also, the findings from the MRI will figure in, since multifocal BC often dictates mastectomy, while a single BC, if not too large, can often be managed with breast conserving surgery (BCS), or lumpectomy.
2. Your full receptor status has not yet been established, due to the inconclusive HER2 results, but since you are ER-/PR-, the eventual outcome will either be "triple negative" (TNBC) or HER2 pos. Both of these tend to be associated with more aggressive cancers (and your cancer cells are Grade 3, which is the most aggressive of the Grades 1-3) which are more likely to spread or recur, so aggressive treatment, including chemo, is usually recommended even when there is no lymph node involvement. (I will add below a link to a recent thread that discusses HER2+ BC.)
Some of our members with this type of cancer have insisted on bilateral mastectomy (with or without reconstructuion) to reduce the possibility of recurrence, even if they were offered the option of lumpectomy. Others choose lumpectomy if that is an option, but follow up with chemo (and Herception if they have HER2+ BC) and radiation, to try to wipe out any possible micrometastases.
I am sorry not to have better news for you, but please keep in mind that recent advancements (such as the use of Herceptin) are improving the outlook for even aggressive types of BC.
Best wishes,
bluebutterfly