hi.
Herceptin is a form of "targeted" therapy for breast cancer. it is basically an antibody against breast cancer with an over expression of the her2/neu gene, and not all breast cancers will be her2 positive. it is a different form of treatment which is usually combined with chemotherapy. and no, i dont think the doctor will look at your nodal status, only the her2/neu.
If you are wanting answers to your questions from the Dr.s employed by the Cleveland Cliinic you should post your question on the "Expert" Forum where those Physicians read and answer questions.