I'm not sure but your Oncologist would have the results of any studies that have been done on these particular circumstances. I do know that many women choose not to take these drugs even though their cancer is ER/PR positive. Regards ....
I was caught early, but with a ER+/PR+, Her2 positive tumor, (no lymph node involvement) I opted to have both breasts removed, TCH chemo, Herceptin for a year, and Tamoxifen.
I have 2-3 hot flashes each day, usually in the evening and no other discernable side effects.
Some people have much more side effects and some have far less. A patient could always try tamoxifen or Arimidex and see how it goes before ruling it out.