The symptoms would depend on the location of the clot. If the clot is in the pulmonary vessel and/or lungs there would be high pulmonary vessel pressure and shortness of breath, right side heart failure, chest pain, etc. If a coronary vessel becomes blocked, there can be chest pain, heart failure, heart arrest. A clot to the vessel going to the brain can cause stroke, coma, death as well a clot to the brain.