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Keppra and Irratibility

my 7 year duaghter has Nocturnal Complex Partial seizures and has been on Keppra liquid for 1 year now.  they just increased her dose to 8 ml in the am and 10 ml in the pm.  she has been extremely grumpy, irritable and very down in the slumps.  Has anybody else experienced this?  the Dr. thinks that she should talk to a Shrink, but I think it all has to do with the medication as she is normally a very happy, loving and caring girl...now she is very pessimistic on EVERYTHING!!!  I don't know what to do and I know that this is not my child's normal behavior...I feel so bad for her and feel guilty for having her to take this medication and feel like this on a day to day basis....any insight from anybody???
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Avatar universal
Just an update on my daughter.  She has been off of Keppra for one month now and WHAT A DIFFERENCE.  We have our old Happy, fun loving little daughter back.  She is no longer grumpy or irritable and she has even noticed a big difference herself.  It is great to see her so happy and loving again.  Taking her off of Keppra was one of the best things that we could have done.  She is now on trileptal and so far, she is a little bit tired, because of the dose increase, but other than that, no side effects. I hope that Trileptal controls her seizures as well as Keppra did...that I will get back to everyone on.  Anyone have any problems with Trileptal?    
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Avatar universal
Hi,

We just went to see my daughter's neuro. today and have finally decided to put her on Trileptal.  As her doage on Keppra increased, so did her irritability and mood swings...She will be weened off of Keppra within the month and will be fully on Trileptal.  Her Neuro. thought this was best, because the B6 just was not helping enough..it helped, but not fully, so now we are on to this med.  I hope it works....i will keep you all posted on this as she gets off of the Keppra.  Hopefully, my bright, happy, cheerful daughter will return.  we gave Keppra a shot, but after two years, we just cannot deal with her mood swings and general unhappiness.  It is not fair to her.  She needs to have a happy childhood. If we see that her mood swings do not get better after thre months of beingon this med, then we, and the Dr. will know that we need to put her on a mood stabilizer, but for now, we all agree that it is the Keppra doing this to her.    
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574101 tn?1245537020
every person will react diffently to meds a lot of dr try the kepera frist because it does not go thought the liver but keep in mind keppra was designed for older people my son was a night mare on keppra
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Avatar universal
My daughters neurologist said the same thing.  It offended me.  I feel the same way you do it is the medicine more than anything.  In some ways the medicine has helped in a lot of ways it makes things worse.  I wished I would have never put her on the medicine.  Her seizures were mild complex partial seizures at night.  I feel i have made a big mistake.  We have tried the vitamin b6 and it did not work.  
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Avatar universal
Hi,

We see one of the top Neurologist in our city, and I asked her.  We started off at 50 mg 1 x a day and are now up to 100mg.  Ask your neurologist.  I know that they have it in a liquid form, but it is hard to find.   Good luck to you and i hope it works. God Bless.  Michele
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Avatar universal
Hi I have a 14 month son who was just recently diagosed with infant generalized epilepsy. He is on 1.5ml of Keppra. He has been on it for 3 weeks now and I have noticed that he cries a lot more for really no reason and he isn't sleeping well. He also has little tamtrums. Who did you ask about the vit.b6? I would like to give me son some but, I don't know if it is safe for him or even how much I could give him.
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