Buffet, if what your wife has is C. diff a 10 day course of flagyl may not be the best therapy for the problem. In many, flagyl doesn't knock out the condition and a specific antibiotic, vancomycin, has to be used.
If you're not working with an infectious disease doc please consider doing so. Many regular physicians are not up-to-date on the problem and it's treatment, and many not be able to knock it out.
I got c-diff June of 2018 they would not test it because it was too thick, had cellulitis and was again put on zoxin got diarrhea again and my doctor tested me and it came back negative. Went on a trip to florida and had accidents in the car, the smell is very distictive. saw doc when I got home he got another sample and put me on vanco. I stopped having stomach problems immediatly althoud test still negative. shortly afterward I was hospitalied it started again. At first they wouldn't test it but it kept getting looser. They did the test it was negative. Appartently they do 2 tests and the 2nd one showed positive. I had so much that after the 9th time changing me in 3 hours they put in a rectal tube. I did nothing but poop for 8 days. Had no appetite and docs didn't know why. I told them it was pretty hard to be hungry when you were sitting there pooping.. finally went home after 2 weeks it was cleared up. This has happened 2 more times. just getting over it again but next time I get antibiotic's I have this problem Thinking about asking for fecal transplant. getting really sick of diapers. als,o did you use probiotics did they work?