48yr old male on hormone replacement therapy for over 10yrs. Being seen for extreme fatigue, loss of concentration, recent ED issues. Blood test exceptions show higher RBC & higher Fe levels as well as low FreeT levels at end of injection cycle. Dr. is considering shortening time between injections from 10 to 7 days or raising dosage from 0.5cc to 0.7cc but concerned about a possible increase to RBC count. Are the higher RBC & higher Fe levels associated with hormone replacement therapy? Hemochromatosis was ruled out by hemotologist but higher RBC reason/causes not really accounted for. Fatigue is severe and along with low FreeT levels point to a definite need for T-injection adjustment. What can be done to mediate/limit a rising RBC if indeed it is associated with hormone replacement therapy?