i dont understand your questioning of this, you took and receive a neg test at 3 months you are in the clear, so get on with life.
The oraquick rapidtest has been shown to be a highly sensitive test. As long as you took it at the appropriate time, it will be accurate.
am i in the clear or not?
thought i would help you with your question with the following"
. ELISA, the most commonly performed diagnostic test in developing countries like India, to detect HIV Antibodies (Ab) is classified on the basis of Antigens (Ag) used.
1st Generation - used infected viral cell lysate as antigen.
2nd Generation - used glycopeptides (recombinant antigens)
3rd Generation - synthetic peptides are used as antigens.
4th Generation, are the newer tests for simultaneous detection of p24 Ag (HIV-1 Ag) and HIV-1/HIV-2Ab.
HIV tests utilizing Recombinant antigens would be 2nd Generation.
Abbot AxSYM test is a 3rd Generation test.
below is also something about the oraquick advance 1/2 test
IndustryHIV testing: an update
Medical Laboratory Observer, Feb, 2008 by Carina Marquez, Nicola M. Zetola, Jeffrey D. Klausner
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Rapid HIV antibody tests
One disadvantage of standard EIAs is that it can take up to two weeks for patients to get results, and many patients in publicly funded testing sites do not return to get their test results. Lack of follow up for test results is a significant problem, and failure to return for test results has been found to occur more frequently among individuals at elevated risk of contracting HIV and individuals who tested positive. (26) Rapid HIV-test results can be received the same day, as testing takes less than 30 minutes to complete, and the test can be done at both clinical and non-traditional sites, such as emergency departments, community centers, and health fairs. In general, rapid tests are preferred by patients in comparison to conventional EIAs, and those tested are more likely to receive their results--especially at non-traditional sites such as needle exchanges or bathhouses. (27,28)
There are four rapid tests cleared for HIV-1/2 detection, one of which, the OraQuick Advance Rapid HIV-1/2 Antibody Test, is cleared for testing of oral fluid (see Table 2). The sensitivity of the tests is comparable to standard second-generation EIA testing. (28) Rapid tests each have a synthetic antigen (the gp41 region of HIV-1, and gp36 for HIV-2) affixed to a test membrane, and a sample (finger-stick blood, venipuncture blood, or oral fluid) is applied to the membrane. If the sample contains antibodies to the gp41 region of HIV, then the membrane will change color. In addition, each test has a goat anti-human IgG antibody for control, and each test requires the periodic use of external controls.
Each rapid test has an assigned Clinical Laboratory Improvement Amendments of 1998 (CLIA'98) category that determines the personnel and the type of facilities required to perform the test. Persons without formal laboratory training and outside the traditional laboratory can perform waived tests. To classify as a CLIA-waived test, the test must use direct, unprocessed specimens (such as oral or whole blood), and must be easy to perform by persons without formal laboratory training. The rapid test is the only HIV-testing modality that can be done outside of the laboratory setting.
Another benefit of the rapid test is that it can be non-invasive, as oral-fluid rapid testing was FDA cleared in 2004. Post-marketing surveillance of the Ora Quick Advance Rapid HIV 1/2 Antibody Test on whole blood and oral fluid yielded favorable results. (29) Testing of over 135,000 whole-blood samples and over 26,000 oral-fluid tests yielded a specificity of 99.98% with a positive predictive value of 99.24% for blood, and specificity of 99.89% with a positive predictive value of 90% for oral fluids. While oral fluid was slightly less specific, experts do not discourage its use, as the increased acceptance of the non-invasive method will likely outweigh the small deficit in specificity. (29)
While data on rapid HIV testing are encouraging, their use still requires some caution. Steckler, et al, (30) reported three cases of early infection that were missed by OraQuick Rapid HIV-1 Antibody Rapid Test, but, subsequently, found to be positive by third-generation EIAs and Western Blots. Although the cases may have been missed due to operator error, those findings support the continued use of RNA pooling within rapid-testing protocols in high-risk populations. Case reports of false-negative test results also emphasize the importance of clinical judgment in the interpretation of negative results.
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i have dealt with my own anxieties ,thank you very much. when you work as close as i do with people who are infected you become hyper vigilant. but i dont need to explain myself to you, i stay because i am good at comforting and because i do research on what i post , you are the one that has been accused of posting false info , i have never. you work in a lab but what is your job, janitor? the question was simple and i have answered it accurately. the end of this conversation, we have higjacked this man thread
There is no reason for you to be giving out advice if you come here asking for advice yourself. There are many third generation HIV tests available in the US, not just Uni-Gold, I could name you 3 or 4 off top of my head. Bottom line: stop posting false information, deal with your own anxieties and move on.
sorry that i also didnt put the antigen sandwich wording in there also but oraquick is not a third gen technology, call them up and they will tell you. its approved to give an accurate result at 3 months which is what the poster i am sure is worried about but once again you dont know what you are talking about.
That is wrong. There are multiple third generation tests currently approved in the US, and Oraquick Advance is almost certainly one of them. Third generation tests are defined by the "antigen sandwich" method, not just IgM detection.
trinity uni gold is the only third gen test approved in the u.s. third gen test look for imG and imM antibodies, oraquick only looks for Im G antibodies. making it comparetive to a second gen test
Oraquick can be compared to III gen
oraquick would equate to 2nd generation technology
Every HIV serology test can be classified by generation.
Oraquick is 3rd generation, I believe
IF they did go by generations, what would you say it is?
Oraquick doesn't go by generations. They rename their tests when they come out with something new.