Is Coenzyme Q10 Good To Take With Dilated Cardiomyopathy

[rarecoolitems]

I have dilated cardiomyopathy with a EF of 35% im wondering if Coenzyme Q10 is good to take. I was also thinking of taking Vitamin E.

Is there anything I should worry about.

[kenkeith]

No,  I don't have a defibrillator.

Remodeling: Heart failure (HF...an EF <30%) is characterized by adverse cardiac structural changes, including myocellular hypertrophy, interstitial disruption, and a reduction in number of cardiac heart cells (myocytes) These changes, collectively called cardiac remodeling, cause chamber enlargement/dysfunction (poor contractility (EF), mediate progression, and predict adverse prognosis in patients with HF.

Treatment: ACE inhibitors (Lisinopril), and even more potently, beta-blockers (Coreg ,my med) , was shown to improve surrogate markers for reverse remodeling, such as ejection fraction (EF), ventricular volumes (chamber size), and mass (wall thickness). For beta-blockers, reverse molecular remodeling was also shown in biopsy specimens on the cellular and subcellular level. Both moderate endurance training and continuous positive airway pressure therapy in heart failure patients induce reverse remodeling.

[rarecoolitems]

Do you have a defibrillator?

How do you "reverse remodeling" Ive never heard that before.

[kenkeith]

According to the Mayo Clinic "CoQ10 has been used, recommended, or studied for numerous conditions, but remains controversial as a treatment in many areas." Further clinical results are needed to determine whether the supplementation with Coenzyme Q10 is beneficial for healthy people.

There is some clinical evidence that supplementation with Coenzyme Q10 is beneficial treatment of patients with congestive heart failure. However, The American College of Cardiology recently published an expert consensus document concluding that the value of coenzyme Q10 in cardiovascular disease has not been clearly established. The Mayo clinic says that there is not enough scientific evidence to recommend for or against the use of CoQ10 in patients with coronary heart disease.

I had a dilated left ventricle and an EF below 29% (heart failure range) going on 6 years.  If your dilated cardomypathy is related to high blood pressure, higher than normal blood volume, etc., and if one effectively treats the underlying cause reducing the heart's workload, the heart size (reverse remodeling) can return to normal size and normalize EF (55-75%).