I have had PVC's frequently for the past 5-6 yrs and it seems to be related to stress and my thyroid condition which bounces back and forth between hyper and hypo thyroidism. I have seen a cadiologist that performed lots of tests and holter monitor, etc. We tried atenolol which lowered my B/P too much, and toprol which made me feel fatigued, and now I am taking bisoprol. The bisoprolol has worked the best but yesterday I woke up with PVC's and then took my medication, and went to see my grandmother in a nursing home. I then started having chest pain that went up my neck and through to my back. I asked the nurse to take my b/p and pulse. My b/p was 110/80 and pulse was 47, she took it eletronically and my b/p was 118/70 and pulse of 48. I wasn't sure what to do so I went back to my parents house and laid down and seemed better after awhile. I am not sure if I should take my pulse before taking the bisoprol and not take if below 60, or keep taking and hope for the best, or what? The chest pain really scared me and I wondered if I had received any damage or it was just lack of blood due to low pulse and pvc's combined. I just wanted you opinion of this episode. Thank you!