Combo Treatment: Baraclude + Viread (results)

[hepbinme]

Hey guys, I'm new to the forum -- I just found the thread through Google by searching Viread + Baraclude. My apologies if I ask a few stupid questions, I'm still learning a lot about HepB. =]

I want to start off by saying that I have been taking both Baraclude + Viread as part of a study in November. I will try to be specific as possible, but all my paperwork and results are back at home since I'm away for college. I'm a 23 year old Asian male and found out I had chronic HepB.

---------------------------------------------------DATA---------------------------------------------------
• 1st blood results were (taken in 07/18/2008). NOT ON TREATMENT
HEPATITIS B VIRAL DNA, QUANT PCR             1,630,000,000 H    <160 copies/mL

• 2nd blood results were (taken in 08/19/2008). NOT ON TREATMENT
HEP B VIRAL DNA QT                                      1,020,000,000 H     <160 copies/mL
                                                *some fluctuation in numbers, but still very high

         ♦I started the combo drugs sometime in November with the high DNA count above, if not more.

• 3rd blood results were (taken in December 2008): ON TREATMENT
HEP B VIRAL DNA QT                                      300,000 H     <160 copies/mL

• 4th blood results were (taken in January 2009): ON TREATMENT
HEP B VIRAL DNA QT                                      801 H    <160 copies/mL

• 5th blood results were (taken in April 2009): ON TREATMENT
HEP B VIRAL DNA QT                                      201 H     <160 copies/mL

My doctor said the goal is to get my HepBeAG to turn negative as it is the engine behind the whole process, and the viral count to Zero.

At the moment, I'm HepBeAB negative, and HepBeAG positive.

Please feel free to ask any questions, and hopefully I'll be able to do the same as well as provide answers.

Thanks everyone! Will keep everyone up to date!

[stef2011]

by the way your goal is prevent cancer and cirrohsis and viread is the most potent antiviral for this, once dna is 0 you are in the same situation as if you have hbs ab...you just need to take a pill to keep this state

consider that when you make hbs ab you still have the virus in the body and also some dna, infact you cannot donate blood/organs even if your hep B is complitely cleared by years

i know a doctor who had hep B and was complitely healed but after taking hep C several years later also hep B came back....

[stef2011]

if your liver has mild fibrosis take something to cure depression

your own body cannot cure infection, if you have hbvdna detectable your body can only help you to die with cancer or cirroshis....

stopping antivirals can be very very dangerous, especially if your liver is damaged already, just talk to your doctor about it maybe you can switch to entecavir but the forum is not the right place for this, your doctor will be able to make the right choice for you

[biobrain]

I have just started taking viread three days before. After Reading all above I am now depressed. In my case I do not have any goal from my treatment as I am already e antigen negetive.

Should I carry on taking viread to lower my viral count or leave it and put myself on natural response of my own body?  As in both cases I have to suffer and die so then why to take treatment?

Can I take herbal medicine and milk thistle alongwith viread?

I am depresed and need motivation from you people.    

[stef2011]

sorry for mistakes:
any adverse event on kidneys?

did you have a liver bipsy or fibroscan at start of treatment?

thank you

[stef2011]

hi, can you also clear with your doctor if you were in the immune tollernat fase when you started or just cronic hbe +
it is very good to see that such high hbv-dna can be suppressed so fast by the combo of most potent antivirals, any adverse event of ?

did you have a liver bipsy or fibroscan at start of treatment kidneys?

thank you

[longman555]

where do you live? I live in Texas not heard about this kind of study.:)