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GS-4774

Has anyone heard anything about Gilead GS-4774?  This is a Tarmogen T cell immunity stimulator.  
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Avatar universal
What is upsetting to see is that companies like Gilead dont listen. You cant even get a responce. No one even comes here and openly engages in a dialog with patients on how can all this be done better.

How to improve clinical trials. That reguar clinical trials are really a joke given so few patients and so.few possibilities in drug combos.
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Shutting down mitochondria in the body is equivalent to power a city lights with power plant reactors turned off. In simple terms that is. But for advancedcancer and HIV that was the choice they had to make. To prolong life. But even with those diseases they admit that immune system gene therapy saves lives. Cancer can be cured better and faster with immune therapy based on  the same Ebola plantibodies treatment and so can HIV.

You design anti viral anti tumor antibodies that multiply within the host body. And nature takes care of it like a common flue or cold.

And they are being silent about this. Doctors dont like hearing about this. That the so called medical standard today when it comes to treat cancer aids and hbv is not where it should be.
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You know looking at it based on what we know it is the immune system of individual that has to do all the work. They are using this vaccine with a nuc. That causes mitochondrial toxicity  thus is immuno suppressive. So the effect that this vaccine could have with interferon or zadaxin may not be there.

Look at Repicor they use it with peg or zadaxin. GS4774 is also said to lower  hbsag. So logically would be to use it with immune system booster. But  no they still want it to be their own brand 1-2 punch.

So this trial may be a wash of nothing in end. But medication may actually work.

I cant say enough how frustrating it is to see ALL the business BS that is going around HBV treatment. Half the time medical students that are doing these clinical trials with their university proffesors have NO clue what so ever what these drugs do to the whole body. That immune system quality depends on the amount if toxins other infections - heath of teeth of a given person.    

That it is not just give the medication and cured. We are not at this Point yet. Unless of course they make antibodies against HBV for us like they did with Ebola.

Why not give GS4774 with Imiqumod. GS9620? That will give a better effect no doubt. Because NUCs really should not be used for HBV. These are really strong and toxic drugs designed to slow down HIV. AND HIV infects every living cell in the body. And so do these drugs.
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Avatar universal
Yes but would Mono be more lucrative? I mean terms of Gileads earnings from this?
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9624973 tn?1413016130
I will ask my doctor, hopefully whe will kniw more about this. But question , is it worthing trying to get this phase 2 trial or better wait for something better
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9624973 tn?1413016130
I am from romania, what are the requirements to qualify for this studi ? I never been on meds and i have very high hbvdna and hbsag and no liver or damage i think.
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