HBeAg negative and HBeAb positive

[bram44]

It appears HBeAg negative and HBeAb positive patients may have core or precore mutations, which results in active replication of virus.

When I had Genotype test it came out as follows :
      Hepatits B virus Genotype    A
     Plymerase mutations            NOT DETECTED
     PRECORE MUTATIONS       NOT DETECTED
     BCP MUTATIONS                NOT DETECTED

Tests also mentioned no resistance predicted for treatment with 5 approved drugs. Did not mention VIREAD in the list, probably being a new drug. I am currently taking VIREAD.

Does this mean I am an inactive carrier ?  

[April63]

Good luck. Let's hope it stays UND forever.:) Please keep us posted.

[cajim]

Good results.

Please keep us updated.

[bram44]

After using VIREAD for a month, my viral DNA became undetectable (from 90,000 copies/ml). Stayed that way so far. I continue to take VIREAD.

With doctor recommendation, I will be stopping medication after 1 year of taking this medicine. After that I will be monitoring AST/ALT every 6 months and DNA every year.

[cajim]

Please don't repeat post.

[mari979]

can anybody help to explain?
I would like to get an information about my husband's hep B blood test results.

hep B core IgM (HBcIgM) - negative
hep B surface Ag (HBsAg) - positive **
HBsAg value              - 6899.00 IU/ML
hep B surface Ab (HBsAb) - negative
hep B surface  Ab value  - >2.0 mIU/ML    0.0 - 10.0
hep B e antigen (HBeAg)  - negative
hep B e antibody (HBeAb) - positive **

I would like to know, how to read this results and what exactly does it mean. Does he have an active infection and is he infectious to others?
He has the virus since a childhood, the doctors say there is no treatment at the moment to get rid of the virus. I am just curious if there is still active virus and if he is infectious to the public. Does it affect the IVF treatment for us - I have been vaccinated and I am immune against hep B virus.
Thank you very much Marianna.

[April63]

Hello. bram44,you've mentioned the genotyping test. My husband had a visit with his doctor yesterday(3 mos. after starting Viread therapy) and asked about it. His VL dropped from about 400 000 UL/ml to just 100 IU/mL. It would be ideal to do the test now,before he goes UND.But the doctor said that this test is only reserved for clinical patients and referral for it,here in Canada, is not jon a walk-in basis. He also added that there have been reported inaccuracies with these test results. I don't know. I'm sort of disappoited that he is not easily available here in Canada. Take care-April