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948882 tn?1270553807

HBeAg negative and HBeAb positive

It appears HBeAg negative and HBeAb positive patients may have core or precore mutations, which results in active replication of virus.

When I had Genotype test it came out as follows :
      Hepatits B virus Genotype    A
     Plymerase mutations            NOT DETECTED
     PRECORE MUTATIONS       NOT DETECTED
     BCP MUTATIONS                NOT DETECTED

Tests also mentioned no resistance predicted for treatment with 5 approved drugs. Did not mention VIREAD in the list, probably being a new drug. I am currently taking VIREAD.

Does this mean I am an inactive carrier ?  
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751470 tn?1268498509
biobrain: in some countries, you just walk into a lab and ask for this test. I had to pay approx €100 for getting it done here.

MEDXIA: what context? And for HbeAg state?
Helpful - 0
948882 tn?1270553807
http://www.hepb.org/pdf/2009_US_Pocket_Guide_Complete_Booklet.pdf

Starting from page 40 (pharmocotherapy) explains treatment guidelines.

For HBeAg negative patients the threshold for treatment is > 2000 IU/ml or >10000 copies/ml.


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Avatar universal
how hight is high and how low is low on DNA viral load in iu/ml?
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948882 tn?1270553807
I think Genotype test needs to be referred by liver specialist.
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Avatar universal

As I learned from this forum any one having HBsAg is in-fact an active carrier. But his/her infection may be low or high based on DNA viral load. If you have a low viral load it mean you are low infectious.  Even when PCR does not detect DNA load virus itself is there in the body and is replicating but at a very low rate. (Please correct me if I am wrong)

I am also HBeAg negative and HBeAb positive. How you have requested these Genotype test and how much it cost. Can anybody go for this or one need a referral from liver specialist?  
Helpful - 0
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