Inteferon + Tenovir : Trial by Gilead

[Bob0620]

End in 2014.
720 participants.

Link : http://clinicaltrials.gov/ct2/show/NCT01277601?term=hiv&lup_s=04%2F13%2F2012&lup_d=30


Try to get info from them as to progress.

[4est]

maybe you should ask what are the condition for participate in another country.

[kinetix1208]

I emailed the POC for this trials and in his reply, he mentioned that Philippines is not included. Thanks for the link.

[4est]

for all location check:

http://clinicaltrials.gov/ct2/show/study/NCT01277601?term=hiv&lup_s=04%2F18%2F2012&lup_d=30&show_locs=Y

click on the "Show 141 Study Locations" and you will see the detailed status for all location. Most of them still recruiting at least in one center:  USA, Canada, France, Germany, Australia, Grace, Hon Kong, Italy, Korea, Nederland, Poland, Portugal, Romania, Singapore, Spain, Taiwan, Turkey, UK

[kinetix1208]

How about other countries that wish to volunteer? Is it possible?

[wph23]

Per Stef2011's suggestions, in order for higher chances of hbsag clearance, we should only do combo therapy after we have hbvdna undetectable AND hbSag is below 1500 iu/ml.

So who should participate in this clinical trial to get the best response for TDF + INF combo?

[Bob0620]

1 - Treatment Arm 1

Subjects will be treated with TDF and PEG concomitantly for 48 weeks.

2.Treatment arm 2

Subjects will be treated with TDF and PEG concomitantly for 16 weeks followed by TDF alone for another 32 weeks (total 48 weeks).

3. Control Arm 1

Subjects will be treated with TDF continuously through 120 weeks.

4. Control Arm 2

Subjects will be treated with PEG for 48 weeks.

[Bob0620]

They are still recruiting patients in Italy, US, germany, Romania. Anyone wishes to volunteer ?